An antihistamine is a drug which serves to reduce or eliminate effects mediated by histamine, an endogenous chemical mediator released during allergic reactions, through action at the histamine receptor.
Only agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines - other agents may have antihistaminergic action but are not true antihistamines.
For more information about the topic Antihistamine, read the full article at Wikipedia.org, or see the following related articles:
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Note: This page refers to an article that is licensed under the GNU Free Documentation License. It uses material from the article Antihistamine at Wikipedia.org. See the Wikipedia copyright page for more details. Editor's Note: This article is not intended to provide medical advice, diagnosis or treatment.
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