Chemotherapy is the use of chemical substances to treat disease.
In its modern-day use, it refers primarily to cytotoxic drugs used to treat cancer.
Cancer is the uncontrolled growth of cells due to damage to DNA (mutations) and, occasionally, due to an inherited propensity to develop certain tumours.
Autoimmune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body; in other words, the body attacks its own cells.
In contrast, transplant rejection happens because a normal healthy human immune system can distinguish foreign tissues and attempts to destroy them.
Also the reverse situation, called graft-versus-host disease, may take place.
Broadly, most chemotherapeutic drugs work by impairing mitosis (cell division), effectively targeting fast-dividing cells.
As these drugs cause damage to cells they are termed cytotoxic.
Some drugs cause cells to undergo apoptosis (so-called "cell suicide").
Arthritis Arthritis is a group of conditions that affect the health of the bone joints in the body. One in three adult Americans suffer from some form of ... >
read more
Bone marrow transplant Bone marrow transplantation (BMT) or hematopoietic stem cell transplantation (HSCT) is a medical procedure in the field of hematology and oncology ... >
read more
Transplant rejection Transplant rejection occurs when the immune system of the recipient of an transplant attacks the transplanted organ or tissue. This is because a ... >
read more
Penicillin-like antibiotics Beta-lactam antibiotics are a broad class of antibiotics which include penicillin derivatives, cephalosporins, monobactams, carbapenems and ... >
read more
Pathogen A pathogen or infectious agent is a biological agent that causes disease or illness to its host. The term is most often used for agents that disrupt ... >
read more
Diabetes mellitus type 1 Type 1 diabetes (formerly known as "childhood" or "juvenile" diabetes or "insulin dependent" diabetes) is most commonly diagnosed in children and ... >
read more
Psoriasis Psoriasis is an immune-mediated disease which affects the skin and joints. It commonly causes red scaly patches to appear on the skin. The scaly ... >
read more
Antiviral drug Antiviral drugs are a class of medication used specifically for treating viral infections. Like antibiotics, specific antivirals are used for ... >
read more
Rheumatoid arthritis Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder that causes the immune system to attack the joints. It is a disabling and ... >
read more
Immune system The immune system is the system of specialized cells and organs that protect an organism from outside biological influences. (Though in a broad ... >
read more