Neanderthals apparently co-existed with anatomically modern humans beginning some 100,000 years ago.
However, about 45,000 years ago, at about the time that stoneworking techniques similar to those of Cro-Magnon people appeared in Europe, Neanderthals began to be displaced.
For more information about the topic Neandertal interaction with Cro-Magnons, read the full article at Wikipedia.org, or see the following related articles:
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