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Sickle-cell disease

Sickle cell disease is a general term for a group of genetic disorders caused by sickle hemoglobin (Hgb S).

In many forms of the disease, the red blood cells change shape upon deoxygenation because of polymerization of the abnormal sickle hemoglobin.

Note: This article excerpts material from the Wikipedia article "Sickle-cell disease", which is released under the GNU Free Documentation License.

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