Sickle cell disease is a general term for a group of genetic disorders caused by sickle hemoglobin (Hgb S).
In many forms of the disease, the red blood cells change shape upon deoxygenation because of polymerization of the abnormal sickle hemoglobin.
For more information about the topic Sickle-cell disease, read the full article at Wikipedia.org, or see the following related articles:
Editor's Note: This article is not intended to provide medical advice, diagnosis or treatment.
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