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New Insights Into Functionality of Cystic Fibrosis Protein
September 26, 2012 — CFTR is an important protein that, when mutated, causes the life-threatening genetic disease cystic fibrosis. A new study details how an accidental discovery has provided new understanding about CFTR ... > full story -
Parents of Babies With Sickle Cell Trait Are Less Likely to Receive Genetic Counseling
September 11, 2012 — Parents of newborns with the sickle cell anemia trait were less likely to receive genetic counseling than parents whose babies are cystic fibrosis carriers, a new study ... > full story -
Human Lungs Brush out Intruders
August 23, 2012 — A new study helps to explain how human airways clear mucus out of the lungs. The findings may give researchers a better understanding of what goes wrong in many human lung diseases, such as cystic ... > full story -
Gene Network Restores Cystic Fibrosis Protein Function
August 1, 2012 — Researchers have discovered a genetic process that can restore function to a defective protein, which is the most common cause of cystic ... > full story -
New Proteins to Clear the Airways in Cystic Fibrosis and COPD
July 13, 2012 — Scientists discovered a new strategy to help CF and COPD patients clear the thick and sticky mucus clogging their lungs, leading to life-threatening infections. The report shows the "SPLUNC1" protein ... > full story -
Exome Sequencing of Health Condition Extremes Can Reveal Susceptibility Genes
July 8, 2012 — Comparing DNA from patients at the best and worst extremes of a health condition can reveal genes for resistance and susceptibly. This approach discovered rare variations in the DCTN4 gene among ... > full story -
Cystic Fibrosis Breakthrough Reveals Why Females Fare Worse Than Males
May 24, 2012 — Researchers have discovered why females with cystic fibrosis do worse than males. The study is the first to show that the female hormone estrogen promotes the presence of a particular form of ... > full story -
Concentrated Saline Therapy Not Effective in Young Children With Cystic Fibrosis
May 21, 2012 — Inhaling concentrated saline (salt water) mist does not reduce how often infants and young children with cystic fibrosis need antibiotics for respiratory symptoms, according to new findings. This ... > full story -
Why One Bacterial Infection Is So Deadly in Cystic Fibrosis Patients: Pathogen Interferes With Cells Whose Job Is to Fight Infection
April 22, 2012 — The bacterium Burkholderia cenocepacia is harmless in healthy people but causes a severe and persistent lung infection in cystic fibrosis patients and is resistant to nearly all known antibiotics. ... > full story -
Computer-Designed Molecules Point to New Therapy for Cystic Fibrosis
April 19, 2012 — By developing software that uses 3-D models of proteins involved in cystic fibrosis, a team of scientists has identified several new molecules that may ease the symptoms of the ... > full story
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