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Gene Regulator in Brain's Executive Hub Tracked Across Lifespan
Scientists have tracked the
activity, across the
lifespan, of an
environmentally responsive
regulatory mechanism that
... > full story
Processes Leading to Acute Myeloid Leukemia Discovered
Researchers have discovered
a molecular pathway that may
explain how a particularly
deadly form of cancer
develops. The discovery may
lead to new cancer therapies
... > full story
First Analysis of Tumor-Suppressor Interactions With Whole Genome in Normal Human Cells Reveals Key Differences With Cancer Cells
Scientists investigating the
interactions, or binding
patterns, of a major
tumor-suppressor protein
known as p53 with the entire
... > full story
Chromosome Centromeres Are Inherited Epigenetically
The histone protein CenH3 is
both necessary and
sufficient to trigger the
formation of centromeres and
pass them on from one
generation to the next. ... > full story
- Gene Regulator in Brain's Executive Hub Tracked Across Lifespan
- Processes Leading to Acute Myeloid Leukemia Discovered
- First Analysis of Tumor-Suppressor Interactions With Whole Genome in Normal Human Cells Reveals Key Differences With Cancer Cells
- Chromosome Centromeres Are Inherited Epigenetically
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Study Maps Destructive Path from Cigarette to Emphysema
January 18, 2012 — Scientists described the track the toxic smoke takes through the tissues and how they accomplish their destructive ... > full story -
New Culprit Discovered in T-Cell Acute Lymphoblastic Leukemia
January 12, 2012 — A new study shows how the cancer causing gene Notch, in combination with a mutated Polycomb Repressive Complex 2 (PRC2) protein complex, work together to cause T- cell acute lymphoblastic leukemia ... > full story -
Scientists Map Susceptibility to Type 2 Diabetes
December 28, 2011 — New research has provided the first proof of molecular risk factors leading to type 2 diabetes, providing an "early warning" sign that could lead to new approaches to treating this and other human ... > full story -
Environment and Diet Leave Their Prints on the Heart
November 29, 2011 — A new study, which set out to investigate DNA methylation in the human heart and the "missing link" between our lifestyle and our health, has now mapped the link in detail across the entire human ... > full story -
Tamoxifen Resistance -- And How to Defeat It
November 13, 2011 — In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the ... > full storyMore: -
Combination 'Epigenetic' Therapy May Restore Anti-Cancer Gene Activity in Late-Stage Lung Cancer Patients
November 10, 2011 — A new type of therapy aimed at reversing the gene-silencing that promotes cancer-cell growth has shown promising results in a small clinical trial. Forty-five late-stage lung cancer patients who ... > full storyMore: -
Study Characterizes Epigenetic Signatures of Autism in Brain Tissue
November 7, 2011 — Neurons in the prefrontal cortex of individuals with autism show changes at numerous sites across the genome, according to a new ... > full story -
Scientists Discover 'Fickle' DNA Changes in Brain
September 30, 2011 — Scientists investigating chemical modifications across the genomes of adult mice have discovered that DNA modifications in non-dividing brain cells, thought to be inherently stable, instead underwent ... > full story -
Women Have Stronger Immune Systems Than Men -- And It's All Down to X-Chromosome Related microRNA
September 27, 2011 — As anyone familiar with the phrase "man-flu" will know women consider themselves to be the more robust side of the species when it comes to health and illness. Now new research seems to support the ... > full story -
Twin Study Reveals Epigenetic Alterations of Psychiatric Disorders
September 21, 2011 — In the first study to systematically investigate genome-wide epigenetic differences in a large number of psychosis discordant twin-pairs, new research provides further evidence that epigenetic ... > full story
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