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Early Life Influences Risk for Psychiatric Disorders
August 18, 2010 For more than a century, clinical investigators have focused on early life as a source of adult psychopathology. Although the hypothesized mechanisms have evolved, a central notion remains: early ... > full story -
Swimming Upstream: Molecular Approaches to Better Understand Male Infertility
August 17, 2010 Male infertility is a common medical problem, affecting millions of men in the United States annually. Its causes include an inability to make productive sperm. Now, using yeast as a model organism, ... > full story -
Scientists Map Epigenetic Changes During Blood Cell Differentiation; Potential Application for Stem Cell Therapies
August 16, 2010 Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, scientists have produced the first-ever ... > full story -
Common Orchid Gives Scientists Hope in Face of Climate Change
August 10, 2010 A study that focuses on epigenetics in European common marsh orchids has revealed that some plants may be able to adapt more quickly to environmental change than previously thought. The research ... > full story -
Diet and Alcohol Alter Epigenetics of Breast Cancer, Study Suggests
July 30, 2010 Researchers have shown that the epigenetic profiles of breast tumors are related to patient diet and alcohol use as well as tumor ... > full story -
Stem Cells Made by Reprogramming Hold Onto Their Past
July 19, 2010 Adult cells that have been reprogrammed into induced pluripotent stem cells (iPS cells) do not completely let go of their past, perhaps limiting their ability to function as a less controversial ... > full story -
New Role for Master Regulator in Cell Metabolism, Response to Stress: Clinical Implications for Obesity, Diabetes and Cancer Research
July 15, 2010 Biologists have been studying how AMPK works for several decades and know that once it is activated, AMPK turns on a large number of genes by passing the "make more energy" message through numerous ... > full story -
New Epigenetic Player Implicated in Mental Retardation and Facial Birth Defects
July 12, 2010 A subtle mutation affecting the epigenome --- a set of dynamic factors that influence gene activity -- may lead to an inherited form of mental retardation that affects boys, researchers have found ... > full story -
Smoking-Related Colorectal Cancer in Older Women Is Associated With Molecularly Defined DNA Changes
June 29, 2010 Smoking, an established risk factor for colon cancer, may induce specific epigenetic changes and gene mutations that may be involved in the development of colon cancer, according to a new ... > full story -
How Embryos Fight Retroviral Infection
June 24, 2010 Some viruses insert themselves into the host's DNA during infection in a process called retroviral integration, causing several diseases, including AIDS and cancer, notes a researcher who specializes ... > full story
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