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Tracking The Molecular Pathway To Mixed-Lineage Leukemia
December 15, 2008 — The MLL-AF4 fusion protein, which causes the blood cancer called mixed-lineage leukemia, binds to several genes responsible for early blood cell development. MLL-AF4 also alters the chromatin ... > full story -
Work With Fungus Uncovering Keys To DNA Methylation
December 15, 2008 — Researchers have made progress on understanding biochemical communications among proteins involved in gene silencing. They have shed more light on the mechanism that regulates DNA methylation, a ... > full story -
Why Are Some People More Susceptible To Depression Than Others? Stressed-out Mice Reveal Role Of Epigenetics In Behavior
December 11, 2008 — Research conducted by a team in Switzerland suggests that a family of genes involved in regulating the expression of other genes in the brain is responsible for helping us deal with external inputs ... > full story -
Changing Epigenetic Modifications That Enable Transposons To Run Amok
December 10, 2008 — Changes in gene activity allow cells to cope with environmental changes but leave genes prone to mis-regulation by transposons -- bits of DNA that jump around the genome, often disrupting normal gene ... > full story -
Novel Histone Demethylase Protein Complex Discovered
December 5, 2008 — Scientists have discovered a novel histone demethylase protein complex characterized in work published in Molecular ... > full story -
Large-Scale Gene Silencing Mystery Solved
December 4, 2008 — Scientists have made a breakthrough in understanding the phenomenon of nucleolar dominance, the silencing of an entire parental set of ribosomal RNA genes in a hybrid plant or animal. Since the ... > full story -
Epigenetics: Plants Display 'Molecular Amnesia'
December 2, 2008 — Plant researchers have announced a major breakthrough in a developmental process called epigenetics. They have demonstrated for the first time the reversal of what is called epigenetic silencing in ... > full story -
Jumonjd3: A Key For Unlocking Neuronal Stem Cell Fate
November 5, 2008 — A novel role for the protein, Jumonjd3, as an epigenetic modulator in the neuronal differentiation of embryonic stem cells, has recently been uncovered -- a step forward in the understanding of ... > full story -
Epigenetics
Pregnancy and Childbirth
Diseases and Conditions
Children's Health
Parkinson's Research
Healthy Aging
Prenatal Exposure To Famine May Lead To Persistent Epigenetic Changes
October 30, 2008 — Prenatal exposure to famine can lead to epigenetic changes that may affect a person's health into midlife. New findings show a trickle-down effect from pregnant women to the DNA of their unborn ... > full story -
Newly Discovered Mechanism Can Explain Beckwith-Wiedemann Syndrome
October 24, 2008 — Researchers have discovered a mechanism that silences several genes in a chromosome domain. The findings, published in Molecular Cell, have implications in understanding the human disorder ... > full story
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