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Dimmer Switch for Regulating Cell's Read of DNA Code
January 9, 2013 — Researchers have been studying the epigenetics enzyme HDAC3 for several years. They discovered that its activity requires interaction with a specific region on another protein called the Deacetylase ... > full story -
In Epigenomics, Location Is Everything: Researchers Exploit Gene Position to Test 'Histone Code'
January 3, 2013 — In a novel use of gene knockout technology, researchers tested the same gene inserted into 90 different locations in a yeast chromosome -- and discovered that while the inserted gene never altered ... > full story -
New Insight Into Cell Development and Cancer
December 27, 2012 — New research has shed new light on how epigenetic signals may function together to determine the ultimate fate of a stem cell. The study implicates a unique class of proteins called polycomb-like ... > full story -
Cancer Study Overturns Current Thinking About Gene Activation
December 18, 2012 — A new Australian study shows that large regions of the genome -- amounting to roughly 2 percent -- are epigenetically activated in prostate cancer. Regions activated contain many prostate ... > full story -
Prickly Holly Reveals Ability to Adapt Genetics to Environmental Change
December 12, 2012 — Prickly holly leaves are a traditional Christmas decoration, from wreaths adorning homes, to greeting card scenes. Yet, look closer at a holly tree and while some leaves are prickly, others are not. ... > full story -
Insight Into DNA Reprogramming During Egg and Sperm Cell Development
December 6, 2012 — Scientists have gained a new understanding of when and how the DNA in developing egg and sperm cells is 'reset', in preparation for making a new ... > full story -
New Evidence for Epigenetic Effects of Diet on Healthy Aging
December 6, 2012 — New research in human volunteers has shown that molecular changes to our genes, known as epigenetic marks, are driven mainly by aging but are also affected by what we eat. The study showed that ... > full story -
Childhood Trauma Leaves Mark on DNA of Some Victims: Gene-Environment Interaction Causes Lifelong Dysregulation of Stress Hormones
December 2, 2012 — Abused children are at high risk of anxiety and mood disorders, as traumatic experience induces lasting changes to their gene regulation. Scientists have now documented for the first time that ... > full story -
Immune System Could Play a Central Role in Age-Related Macular Degeneration
November 28, 2012 — Changes in how genes in the immune system function may result in age-related macular degeneration (AMD), the leading cause of visual impairment in older adults. The findings are epigenetic in nature, ... > full story -
Short DNA Strands in Genome May Be Key to Understanding Human Cognition and Diseases
November 21, 2012 — Previously discarded, human-specific “junk” DNA represents untapped resource in the study of diseases like Alzheimer’s and ... > full story
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