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Light Shed on Complexity of Gene Therapy for Congenital Blindness
January 21, 2013 — Independent clinical trials have reported safety and efficacy for Leber congenital amaurosis (LCA), a congenital form of blindness caused by mutations in a gene (RPE65) required for recycling vitamin ... > full story -
Quantum Leap in Gene Therapy of Duchenne Muscular Dystrophy
January 15, 2013 — For years, scientists have been working to find the key to restoring dystrophin, but they have faced many challenges. After careful evaluation of 22 dogs, researchers found that the new version of ... > full story -
Researchers Identify a New Gene With a Key Role in Obesity and Diabetes
January 10, 2013 — An international team of scientists has identified a gene which regulates fat metabolism and is involved in the onset of obesity and related metabolic disorders like type 2 diabetes. The researchers ... > full story -
In Epigenomics, Location Is Everything: Researchers Exploit Gene Position to Test 'Histone Code'
January 3, 2013 — In a novel use of gene knockout technology, researchers tested the same gene inserted into 90 different locations in a yeast chromosome -- and discovered that while the inserted gene never altered ... > full story -
Gene Variation May Shape Bladder Cancer Treatment, Study Suggests
January 3, 2013 — Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many ... > full story -
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Rebuilding Blood Vessels Through Gene Therapy
December 21, 2012 — Diagnosed with severe coronary artery disease, a group of patients too ill for or not responding to other treatment options decided to take part in a clinical trial testing angiogenic gene therapy to ... > full story -
Serendipity Points to New Potential Target and Therapy for Melanoma
December 20, 2012 — A new study describes a new target and potential treatment for melanoma, the most dangerous form of skin cancer. MicroRNA can decide which genes in a cell's DNA are expressed and which stay silent. ... > full story -
First Use of a Gene Therapy Shows Promise Against Fatal Childhood Disease
December 19, 2012 — There are promising results from the first-ever use of a virus-based gene therapy for a neurodegenerative/neurological disorder. The therapy was given to 19 young patients with Canavan disease, a ... > full story -
First Gene Therapy Study in Human Salivary Gland Shows Promise
November 5, 2012 — This finding comes from the first-ever Phase I clinical study of gene therapy in a human salivary gland. Its results show that the transferred gene, Aquaporin-1, has great potential to help head and ... > full story -
Genetic Predictors of Fatigue for Prostate Cancer Patients Receiving Androgen Deprivation Therapy
October 26, 2012 — Researchers have found that men with prostate cancer who receive androgen deprivation therapy may predictably suffer from fatigue if they have single nucleotide polymorphisms in three ... > full story
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