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Gene Variation May Shape Bladder Cancer Treatment, Study Suggests
January 3, 2013 — Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many ... > full story -
Gene Therapy
Heart Disease
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Rebuilding Blood Vessels Through Gene Therapy
December 21, 2012 — Diagnosed with severe coronary artery disease, a group of patients too ill for or not responding to other treatment options decided to take part in a clinical trial testing angiogenic gene therapy to ... > full story -
Serendipity Points to New Potential Target and Therapy for Melanoma
December 20, 2012 — A new study describes a new target and potential treatment for melanoma, the most dangerous form of skin cancer. MicroRNA can decide which genes in a cell's DNA are expressed and which stay silent. ... > full story -
First Use of a Gene Therapy Shows Promise Against Fatal Childhood Disease
December 19, 2012 — There are promising results from the first-ever use of a virus-based gene therapy for a neurodegenerative/neurological disorder. The therapy was given to 19 young patients with Canavan disease, a ... > full story -
First Gene Therapy Study in Human Salivary Gland Shows Promise
November 5, 2012 — This finding comes from the first-ever Phase I clinical study of gene therapy in a human salivary gland. Its results show that the transferred gene, Aquaporin-1, has great potential to help head and ... > full story -
Genetic Predictors of Fatigue for Prostate Cancer Patients Receiving Androgen Deprivation Therapy
October 26, 2012 — Researchers have found that men with prostate cancer who receive androgen deprivation therapy may predictably suffer from fatigue if they have single nucleotide polymorphisms in three ... > full story -
New Anti-Tumor Cell Therapy Strategies Are More Effective
October 25, 2012 — Targeted T-cells can seek out and destroy tumor cells that carry specific antigen markers. Two novel anti-tumor therapies that take advantage of this T-cell response are described in two new ... > full story -
Gene Polymorphisms Identified That Are Responsible for Breast Density and Cancer Risk
October 23, 2012 — It has long been known that breast density, or mammographic density, is a strong risk factor for breast cancer, and that estrogen and progestin hormone therapy increases dense breast tissue. Now, a ... > full story -
New Treatment Method for Children With Brain Tumours
October 15, 2012 — Children who undergo brain radiation therapy run a significant risk of suffering from permanent neurocognitive adverse effects. These adverse effects are due to the fact that the radiation often ... > full story -
Shape Matters in DNA Nanoparticle Therapy: Particles Could Become a Safer, More Effective Delivery Vehicle for Gene Therapy
October 12, 2012 — Researchers have discovered how to control the shape of nanoparticles that move DNA through the body and have shown that the shapes of these carriers may make a big difference in how well they work ... > full storyMore:
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