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A Cautionary Tale on Genome-Sequencing Diagnostics for Rare Diseases
May 10, 2013 — Researchers have discover that several children born with rare diseases called congenital disorders of glycosylation don't contain the mutation in every cell type -- raising new questions about ... > full story -
Justinianic Plague Was Caused by Bacterium Yersinia Pestis, DNA of Skeletal Remains Shows
May 10, 2013 — Ancient DNA analyses of skeletal remains of plague victims from the 6th century AD provide information about the phylogeny and the place of origin of this ... > full story -
Gene Associated With Eczema in Dogs Identified
May 9, 2013 — A novel gene associated with canine atopic dermatitis has been identified. The gene encodes a protein called plakophilin 2, which is crucial for the formation and proper functioning of the skin ... > full story -
Gene Identified, Responsible for a Spectrum of Disorders Affecting the Bones and Connective Tissue
May 9, 2013 — Researchers have identified a gene that when mutated is responsible for a spectrum of disorders affecting the bones and connective tissue. This finding opens new avenues for research into a diagnosis ... > full story -
Epigenomics of Stem Cells That Mimic Early Human Development Charted
May 9, 2013 — Scientists have long known that control mechanisms known collectively as “epigenetics” play a critical role in human development, but they did not know precisely how alterations in this ... > full story -
Mapping the Embryonic Epigenome: How Genes Are Turned on and Off During Early Human Development
May 9, 2013 — A large, multi-institutional research team has published a sweeping analysis of how genes are turned on and off to direct early human ... > full story -
Research Reveals Cancer-Suppressing Protein 'Multitasks'
May 9, 2013 — The understanding of how a powerful protein called p53 protects against cancer development has been upended by a new ... > full story -
Studies Generate Comprehensive List of Genes Required by Innate System to Defend Sex Cells
May 9, 2013 — Investigators have published studies revealing many previously unknown components of an innate system that defends sex cells -- the carriers of inheritance across generations -- from the ravages of ... > full story -
Dad's Genome More Ready at Fertilization Than Mom's Is -- But Hers Catches Up
May 9, 2013 — Researchers have discovered that while the genes provided by the father arrive at fertilization pre-programmed to the state needed by the embryo, the genes provided by the mother are in a different ... > full story -
Genes Define the Interaction of Social Amoeba and Bacteria
May 9, 2013 — Researchers have used the model of the social amoeba -- Dictyostelium discoideum -- to identify the genetic controls on how the amoeba differentiate the different bacteria and respond to achieve ... > full story
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