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Drug Shows Surprising Efficacy as Treatment for Chronic Leukemia, Mantle Cell Lymphoma
June 19, 2013 — Clinical studies suggest that the novel, targeted agent ibrutinib shows real potential is a safe, effective, treatment for adults with chronic lymphocytic leukemia and for patients with mantle cell ... > full story -
'Undruggable' Cancer May Be Druggable After All: New Target Identified
June 17, 2013 — Researchers have identified in the most aggressive forms of cancer a gene known to regulate embryonic stem cell self-renewal, beginning a creative search for a drug that can block its ... > full story -
Epigenetic Factor Likely Plays a Key Role in Fueling Most Common Childhood Cancer
June 10, 2013 — Changes in an epigenetic mechanism that turns expression of genes on and off may be as important as genetic alterations in causing pediatric acute lymphoblastic leukemia, according to a new ... > full story -
Normal Molecular Pathway Affected in Poor-Prognosis Childhood Leukemia Identified
June 6, 2013 — Through genetic engineering of laboratory models, researchers have uncovered a vulnerability in the way cancer cells diverge from normal regenerating cells that may help treat children with ... > full story -
Genetic Testing of Rare Blood Cancer Reveals New Mutation
June 5, 2013 — A recent article describes genetic testing of a rare blood cancer called atypical chronic neutrophilic leukemia that revealed a new mutation present in most patients with the ... > full story -
Significantly Improved Survival Rates for Stem Cell Transplant Recipients
May 28, 2013 — Study of 38,000 blood stem cell transplant recipients shows that survival rates increased significantly over 12 years, and numbers of patients receiving transplants grew ... > full story -
Findings May Help Overcome Hurdle to Successful Bone Marrow Transplantation
May 28, 2013 — Blood diseases such as leukemia, multiple myeloma, and myelodysplasia can develop from abnormal bone marrow cells and a dysfunctional bone marrow microenvironment that surrounds these cells. ... > full story -
GATA-3 Is Important for Regulation and Maintenance of Immune System
May 27, 2013 — The protein GATA-3 plays an important role in mammalian immune response, but its overall function in cell development and cancer formation is not well understood. In an effort to further define the ... > full story -
Discarded Immune Cells Induce the Relocation of Stem Cells
May 23, 2013 — The study reveals a surprising coordination between two fundamental body systems, the immune and the hematopoietic. The study has implications for the understanding of metastasis, because malignant ... > full story -
Keeping Stem Cells Strong: RNA Molecule Protects Stem Cells During Inflammation
May 21, 2013 — A team of researchers led by biologists at the California Institute of Technology has found that, in mouse models, the molecule microRNA-146a acts as a critical regulator and protector of ... > full story
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