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Making Gene Therapy Safer Using Self-Inactivating LTRs
March 24, 2009 — Several patients in gene therapy clinical trials have developed leukemia as a result of their treatment. The underlying cause of leukemia is thought to be that the viral vectors used to carry the ... > full story -
Insight Into How A Fusion Gene Promotes Childhood Leukemia
March 16, 2009 — Fusion of the genes TEL and AML1 to form the TEL-AML1 fusion gene is a frequent genetic abnormality in childhood acute lymphoblastic leukemia. This mutation usually occurs before birth but can remain ... > full story -
Genetic Abnormality May Increase Risk Of Blood Disorders
March 15, 2009 — Researchers have shown for the first time that a tendency to develop some blood disorders may be inherited. Their research identifies a common genetic sequence abnormality that enhances the ... > full story -
Cellular Discovery May Lead To Targeted Treatment For Rare Form Of Anemia
March 15, 2009 — University of Cincinnati researchers have identified the specific biological mechanisms believed to lead to a rare and incurable blood disease known as Diamond Blackfan anemia. Scientists say with ... > full story -
Small Molecules Block Cancer Gene
March 10, 2009 — Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared ... > full story -
Few Physicians Support Private Banking Of Umbilical Cord Blood
March 6, 2009 — A survey of physicians has found broad support for the position that parents should not bank their newborns' umbilical cord blood in a private blood bank unless another member of the family is at ... > full story -
How Stem Cells Develop Into Blood Cells
March 5, 2009 — How messages sent within stem cells through a specific communication pathway can trigger the cells to specialize and become blood cells in humans has been discovered by scientists of the McMaster ... > full story -
Indicator Found That Warns Leukemia Is Progressing To More Dangerous Form
February 17, 2009 — Scientists have identified a mechanism by which a chronic form of leukemia can progress into a deadlier stage of the disease. The findings may provide physicians with an indicator of when this type ... > full story -
Device Aims To Decrease Wait Period For Patients Needing Immunotherapy
February 13, 2009 — Researchers have created a device that significantly decreases the time needed to produce genetically manipulated T cells in preclinical tests for ... > full story -
Unrelated And Mismatched Cord Blood Transplantation Can Still Help Children With Deadly Conditions
February 13, 2009 — An unrelated cord blood transplant, even from a mismatched donor, can be effective in treating children with a host of life-threatening diseases and disorders including cancer, sickle cell anemia, ... > full story
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