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Stem Cells: Deathly Awakening By Interferon
February 12, 2009 — Interferon-alpha, a messenger substance of the immune system, awakens dormant hematopoietic stem cells in the bone marrow to become active, thus making them vulnerable for the effect of many drugs. ... > full story -
Bone Marrow Transplant Patients May Benefit From New Immune Research
February 11, 2009 — Bone marrow transplant researchers may have found a mechanism that could preserve the leukemia-killing effects of a transplant graft, while limiting the damage donor immune cells might do to the ... > full story -
First Genome-Wide Expression Analysis Yields Better Understanding Of How Leukemia Develops
February 9, 2009 — Scientists have performed a genome-wide expression analysis comparing highly enriched normal blood stem cells and leukemic stem cells, and identified several new pathways that have a key role in ... > full story -
New Genes Involved In Acute Lymphoblastic Leukemia Play Fundamental Role In Prognosis Of The Disease
February 6, 2009 — The inactivity or “silence” of certain genes plays a fundamental role in the prognosis of acute lymphoblastic leukemia (ALL) as well as in response to treatment, according to a new ... > full story -
Leukemia Stem Cells Have More In Common With Embryonic Stem Cells Than Adult Stem Cells
February 5, 2009 — Research using a mouse model of human leukemia has provided critical insight into the genetic factors related to the generation and maintenance of myeloid leukemia stem cells. The study is likely to ... > full story -
Stem Cells And ABC Transporters Essential In Kidney Regeneration
January 28, 2009 — Scientists have found that stem cells and ABC transporter proteins are indispensable for tubular regeneration after acute kidney ... > full story -
Bone Marrow Cells Help Repair Damaged Lung
January 26, 2009 — Scientists have identified a population of mouse bone marrow cells that can contribute to repair of the injured lung. As cells expressing similar markers were identified in human bone marrow, the ... > full story -
Cell's Inactive State Is Critical For Effectiveness Of Cancer Treatment
January 9, 2009 — A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or ... > full story -
Gene Abnormality Found To Predict Childhood Leukemia Relapse
January 7, 2009 — Scientists have identified mutations in a gene that predict a high likelihood of relapse in children with acute lymphoblastic leukemia (ALL). Although the researchers caution that further research is ... > full story -
'Relocation' Plan Of Metastatic Cancer Cells Uncovered
January 5, 2009 — Few things are as tiresome as house hunting and moving. Unfortunately, metastatic cancer cells have the relocation process down pat. Tripping nimbly from one abode to another, these migrating cancer ... > full story
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