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Study Maps Destructive Path from Cigarette to Emphysema
January 18, 2012 — Scientists described the track the toxic smoke takes through the tissues and how they accomplish their destructive ... > full story -
Precancer Markers Identified in Airway Epithelium Cells of Healthy Smokers
January 11, 2012 — Smokers are more likely to have molecular features of cancerization in the large airway epithelium. Smokers with COPD had significant changes in the small airway epithelium, new research has shown. ... > full story -
Ganetespib Showed Activity in KRAS-Mutant NSCLC as Monotherapy and in Combinations
January 11, 2012 — Novel Hsp90 inhibitor shows activity in slowing KRAS-mutant NSCLC tumor cell growth. Use with traditional chemotherapy resulted in increased cancer cell death. Phase 2b/3 trial combined with ... > full story -
Predicting Which Lung Cancer Drugs Are Most Likely to Work
January 10, 2012 — Researchers have shown that DNA changes in a gene that drives the growth of a form of lung cancer can make the cancer’s cells resistant to cancer drugs. The findings show that some classes of ... > full story -
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Sorafenib Effective in Patients With Non-Small Cell Lung Cancer, but Low Survival Rates Reported
January 9, 2012 — Sorafenib was effective in patients with non-small cell lung cancer and a KRAS mutation, but survival rates were reportedly "unsatisfactory," according to new ... > full story -
Researchers Map Potential Genetic Origins, Pathways of Lung Cancer in Never-Smokers
January 9, 2012 — Researchers have begun to identify which mutations and pathway changes lead to lung cancer in never-smokers -- a first step in developing potential therapeutic ... > full story -
Genetic Composition of Multicentric Lung Tumors Appears to Be Similar
January 9, 2012 — Multicentric carcinogenesis with the same genetic mutation appears to occur in lung adenocarcinoma, according to new ... > full story -
Estrogen-Targeting Drug Combo May Help Prevent Lung Cancer
January 9, 2012 — A combination of drugs that target estrogen production significantly reduced the number of tobacco carcinogen-induced lung tumors in mice, according to results from a preclinical ... > full story -
Sensitive Detection Method Analyzes Circulating Tumor Cells in Patients With Lung Cancer
January 9, 2012 — Researchers have developed a method to analyze circulating tumor cells in the blood of patients with non-small cell lung cancer. This method, which can analyze a sample size as small as three cells, ... > full story -
Malignancy-Risk Gene Signature for Early-Stage Non-Small Cell Lung Cancer Found
January 6, 2012 — A malignancy-risk gene signature developed for breast cancer has been found to have predictive and prognostic value for patients with early stage non-small cell lung ... > full story
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