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PET Scan With [11C]erlotinib May Provide Noninvasive Method to Identify TKI-Responsive Lung Tumors
July 5, 2011 — A non-invasive PET imaging technique may identify lung cancers that respond best to tyrosine kinase inhibitors (TKIs), allowing doctors to better select patients for personalized therapy, according ... > full story -
EURTAC Phase III Study: Erlotinib Nearly Doubles Progression-Free Survival Vs. Chemotherapy
July 5, 2011 — In the first phase III study to include Western lung cancer patients, first-line treatment with erlotinib (Tarceva) nearly doubled progression-free survival compared with chemotherapy, according to ... > full story -
Lung Tumors in Never-Smokers Show Greater Genomic Instability Than Those in Smokers
July 5, 2011 — Lung adenocarcinomas in people who have never smoked show greater genome instability than those in smokers, supporting the theory that lung cancer in never smokers arises through different pathways, ... > full story -
ALK Rearrangement Found in Nearly 10 Percent of Patients in Lung Cancer Mutation Consortium
July 5, 2011 — ALK rearrangement has been found in 9.6 percent of lung cancer patients tested in the Lung Cancer Mutation Consortium, and MET amplification in another 4.1 percent, reflecting how many patients might ... > full story -
High EGFR Expression a Predictor for Improved Survival With Cetuximab Plus Chemotherapy
July 5, 2011 — High epidermal growth factor receptor (EGFR) expression was a good predictor of which lung cancer patients would survive longer when cetuximab (Erbitux) was added to first-line chemotherapy, ... > full story -
CT Scans Unleash a Breakthrough in Catching Early Stage Lung Cancer
June 30, 2011 — The National Lung Screening Trial (NLST) is the first scientific study that provides clear evidence that CT screening significantly reduces the death rate due to lung cancer. NLST data shows 20 ... > full story -
Screening With Low-Dose Spiral CT Scanning Reduces Lung Cancer Deaths by 20 Percent
June 29, 2011 — Current or heavy smokers who were screened with low-dose spiral computed tomography (CT) scanning had a 20 percent reduction in deaths from lung cancer than did those who were screened by chest ... > full story -
Lung Cancer Screening Program: Experts Mobilize After National Clinical Trial Shows CT Scanning Reduces Deaths by 20 Percent
June 29, 2011 — Current and former heavy smokers can now be screened more effectively for lung cancer. Results from the National Lung Screening Trial revealed that detecting small lung cancers with computed ... > full story -
Blocking Molecular Target Could Make More Cancers Treatable With PARP Inhibitors
June 29, 2011 — Researchers have demonstrated a molecular strategy they say could make a much larger variety of tumors treatable with PARP inhibitors, a promising new class of cancer drugs. They report that the ... > full story -
Stem Cell Scientists Discover New Airway Stem Cell
June 27, 2011 — Researchers have identified a new stem cell that participates in the repair of the large airways of the lungs, which play a vital role in protecting the body from infectious agents and toxins in the ... > full story
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