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Two Proteins Play Key Roles in Burkitt's Lymphoma
March 7, 2011 — A new study reveals new molecular insight into the understanding and treatment of Burkitt`s lymphoma, one of the most aggressive tumors affecting ... > full story -
Cancer-Causing Virus Exploits Key Cell-Survival Proteins
February 22, 2011 — The human T-lymphotropic virus type 1, a cancer-causing retrovirus, exploits key proteins in host cells to extend the life of those cells, thereby prolonging its own survival and ability to spread, ... > full story -
Novel Immune System-Based Gene Therapy Induces Strong Responses in Metastatic Melanoma, Sarcoma
January 31, 2011 — Researchers have found that a novel form of personalized therapy that genetically engineers a patient's own anti-tumor immune cells to fight tumors could treat metastatic melanoma and metastatic ... > full story -
Lymphoma
Computer Science
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Today's Healthcare
Medical Imaging
Computer-Assisted Diagnosis Tools to Aid Pathologists
January 31, 2011 — Researchers are leveraging powerful Ohio Supercomputer Center resources to develop computer-assisted diagnosis tools for diagnosing Follicular Lymphoma. Accurate grading of the pathological samples ... > full story -
How Fusion Protein Triggers Cancer
January 27, 2011 — What happens when two proteins join together? In this case, they become like a power couple, where the whole is greater than the sum of the parts. The fusion protein API2-MALT1 joins with the enzyme ... > full story -
Many Cancer Cells Found to Have an 'Eat Me' Signal
December 22, 2010 — Researchers have discovered that many cancer cells carry the seeds of their own destruction -- a protein on the cell surface that signals circulating immune cells to engulf and digest them. On cancer ... > full story -
Epstein-Barr: Scientists Decode Secrets of a Very Common Virus That Can Cause Cancer
December 15, 2010 — About 90 percent of people are infected at some time in their lives with Epstein-Barr virus (EBV), usually with no ill effects. But individuals with compromised immune systems, such as people with ... > full story -
Aggressive Blood Cancers: Is Pralatrexate Effective in Patients With T-Cell Lymphoma Who Fail ICE-Based Regimens?
December 7, 2010 — Researchers analyzed data from the phase II pivotal trial of pralatrexate (known as the PROPEL study) -- which led to the FDA approval of pralatrexate in September 2009. Forty percent of study ... > full story -
Aggressive Blood Cancers: Adoptive Transfer of Treg-Depleted Donor Th1 and Th2 Cells Safely Accelerates Alloengraftment After Low-Intensity Chemotherapy
December 7, 2010 — Researchers conducted a clinical trial to evaluate the effectiveness of infusing cultured donor immune cells known as "T-rapa" cells after stem cell transplantation into patients being treated for ... > full story -
Drug Resistance of Chronic Lymphocytic Leukemia in Bone Marrow and Lymph Nodes
December 6, 2010 — Scientists now offer a new explanation of why chronic lymphocytic leukemia (CLL) tends to recur in the lymph nodes and bone marrow after being cleared from the bloodstream by ... > full story
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