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Novel Immune System-Based Gene Therapy Induces Strong Responses in Metastatic Melanoma, Sarcoma
January 31, 2011 Researchers have found that a novel form of personalized therapy that genetically engineers a patient's own anti-tumor immune cells to fight tumors could treat metastatic melanoma and metastatic ... > full story -
Lymphoma
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Medical Imaging
Computer-Assisted Diagnosis Tools to Aid Pathologists
January 31, 2011 Researchers are leveraging powerful Ohio Supercomputer Center resources to develop computer-assisted diagnosis tools for diagnosing Follicular Lymphoma. Accurate grading of the pathological samples ... > full story -
How Fusion Protein Triggers Cancer
January 27, 2011 What happens when two proteins join together? In this case, they become like a power couple, where the whole is greater than the sum of the parts. The fusion protein API2-MALT1 joins with the enzyme ... > full story -
Many Cancer Cells Found to Have an 'Eat Me' Signal
December 22, 2010 Researchers have discovered that many cancer cells carry the seeds of their own destruction -- a protein on the cell surface that signals circulating immune cells to engulf and digest them. On cancer ... > full story -
Epstein-Barr: Scientists Decode Secrets of a Very Common Virus That Can Cause Cancer
December 15, 2010 About 90 percent of people are infected at some time in their lives with Epstein-Barr virus (EBV), usually with no ill effects. But individuals with compromised immune systems, such as people with ... > full story -
Aggressive Blood Cancers: Is Pralatrexate Effective in Patients With T-Cell Lymphoma Who Fail ICE-Based Regimens?
December 7, 2010 Researchers analyzed data from the phase II pivotal trial of pralatrexate (known as the PROPEL study) -- which led to the FDA approval of pralatrexate in September 2009. Forty percent of study ... > full story -
Aggressive Blood Cancers: Adoptive Transfer of Treg-Depleted Donor Th1 and Th2 Cells Safely Accelerates Alloengraftment After Low-Intensity Chemotherapy
December 7, 2010 Researchers conducted a clinical trial to evaluate the effectiveness of infusing cultured donor immune cells known as "T-rapa" cells after stem cell transplantation into patients being treated for ... > full story -
Drug Resistance of Chronic Lymphocytic Leukemia in Bone Marrow and Lymph Nodes
December 6, 2010 Scientists now offer a new explanation of why chronic lymphocytic leukemia (CLL) tends to recur in the lymph nodes and bone marrow after being cleared from the bloodstream by ... > full story -
Personalized Vaccine for Lymphoma Patients Extends Disease-Free Survival by Nearly 2 Years
December 6, 2010 A personalized vaccine is a powerful therapy to prevent recurrence among certain follicular lymphoma patients, according to the latest results. When these patients -- whose tumors are marked by a ... > full story -
New Standards of Care and Novel Treatment Options for Several Forms of Lymphoma Unveiled
December 6, 2010 New research points to promising new options for the standard treatment of advanced asymptomatic follicular lymphoma, mantle cell lymphoma, and early, unfavorable Hodgkin disease. Other research ... > full story
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