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Scientists Combine Targeted Agents to Kill Multiple Myeloma Cells
February 10, 2011 — Scientists have developed a novel treatment strategy for multiple myeloma that pairs two targeted agents to kill cancer ... > full story -
How Cancer Gene MMSET Functions
February 2, 2011 — For several decades, researchers have been linking genetic mutations to diseases ranging from cancer to developmental abnormalities. What hasn't been clear, however, is how the body's genome sustains ... > full story -
Multiple Myeloma
Multiple Sclerosis Research
Leukemia
Cancer
Diseases and Conditions
Personalized Medicine
Drug Combination Shows Promise for Newly Diagnosed Blood Cancer Patients, Study Finds
December 9, 2010 — A new three-drug combination used to treat the blood cancer multiple myeloma may be effective as a front-line therapy for newly diagnosed patients, according to a new ... > full story -
Leukemia
Cancer
Multiple Sclerosis Research
Today's Healthcare
Diseases and Conditions
Wounds and Healing
Phase 2 Study of MLN8237: Investigational Aurora A Kinase (Aak) Inhibitor in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndromes (MDS)
December 7, 2010 — Aurora A kinase is essential for cell division (mitotic progression) and is amplified or overexpressed in AML and other blood cancers. An investigational drug, MLN8237 is an orally available, potent, ... > full story -
Aggressive Blood Cancers: Response of Multiple Myeloma Patients to Carfilzomib After Other Treatments Have Failed
December 7, 2010 — A new proteasome inhibitor may hold hope for patients with multiple myeloma who have been treated unsuccessfully with other drugs. The medication has already demonstrated antitumor activity in phase ... > full story -
Aggressive Blood Cancer: Clinical Trial of Lenalidomide Plus Dexamethasone Followed by Autologous Stem Cell Transplantation (ASCT) in Multiple Myeloma
December 7, 2010 — A new transplantation technique, which uses a patient's own adult stem cells, has been a first-line treatment for patients who are newly diagnosed with certain blood cancers. Multiple myeloma is a ... > full story -
Key Molecules in Multiple Myeloma Identified
October 26, 2010 — New research links three molecules to a critical tumor suppressor gene that is often turned off in multiple myeloma. The findings might offer a new strategy for treating this incurable disease and ... > full story -
High Response Rates Seen in Phase-III Trial of Chemotherapy, New Drug and Stem Cells in Myeloma
October 12, 2010 — The first study of its kind comparing two different approaches to treating newly diagnosed multiple myeloma has found that both treatments achieved a positive response, researchers ... > full story -
Role of DNA Methylation in Multiple Myeloma Blood Cancer Identified
September 30, 2010 — DNA methylation -- a modification of DNA linked to gene regulation -- is altered with increasing severity in a blood cancer called multiple myeloma, according to a new ... > full story -
Study Describes Health Effects of Occupational Exposures in Paducah Gaseous Diffusion Plant Workers
July 22, 2010 — A five-year study into the causes of deaths of workers at Paducah Gaseous Diffusion Plant shows significantly lower death rates from all causes and cancer in general when compared to the overall ... > full story
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