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Mighty Mice Are Less Susceptible To Muscular Dystrophy Gene's Effects
November 26, 2002 — The Johns Hopkins scientists who first discovered that knocking out a particular muscle gene results in "mighty mice" now report that it also softens the effects of a genetic mutation that ... > full story -
Gene Therapy Reverses Muscular Dystrophy In Animal Model
September 17, 2002 — Researchers have proven that gene therapy can reverse the pathological features of muscular dystrophy in an animal model. Before, gene therapy had only been able to prevent further muscle-wasting in ... > full story -
UT Southwestern Researchers Decode Filament Structures That Help Organize Signaling Molecules In Cells
August 22, 2002 — Scientists at UT Southwestern Medical Center at Dallas have found the blueprint for how filaments assemble during the development of caveolae, a membrane system that organizes signaling molecules ... > full story -
Scientists Identify A New Kind Of Genetic Problem In Muscular Dystrophy
August 12, 2002 — A newly identified genetic problem underlies a common neuromuscular disorder called facioscapulohumeral muscular dystrophy (FSHD), scientists say. In a new study, they show that deletion of ... > full story -
Studies Find Molecular Basis For Brain Defects In Certain Muscular Dystrophies
July 29, 2002 — Piecing together a biochemical and genetic puzzle, University of Iowa researchers and their colleagues have revealed a new molecular mechanism that appears to be the root cause of a subset of ... > full story -
Researchers Identify Defect That Causes Rare Muscular Dystrophies
July 25, 2002 — Subtle defects in the processing of a single protein that provides structural integrity to muscle cells can lead to several devastating forms of muscular dystrophy, according to studies by Howard ... > full story -
Muscle Stem Cells Show Promise Against Muscular Dystrophy In Mouse Model
July 4, 2002 — Scientists have isolated special muscle-generating stem cells that can improve muscle regeneration and deliver the missing protein dystrophin to damaged muscles in a mouse muscular dystrophy (MD) ... > full story -
Muscular Dystrophy Mouse Model Yields Potential Growth Factor Treatment
May 23, 2002 — An altered mouse model of Duchenne muscular dystrophy, developed to have high levels of insulin-like growth factor I (IGF-I), has shown increases in muscle mass of at least 40 percent and other ... > full story -
Cell Transplantation Delivers Key Protein To Mice With Muscle-Wasting Condition Similar To Duchenne Muscular Dystrophy
May 21, 2002 — Transplanting a unique population of muscle stem cells from healthy newborn mice delivers dystrophin, a key protein for muscle function, into mice born with a genetic muscle-wasting disease similar ... > full story -
Scientists Identify DNA Flanking Region As Trigger For Genetic Instability
April 22, 2002 — Scientists at The Hospital for Sick Children and the University of Toronto have shown that the DNA flanking region in a family of neurological disorders is triggering the genetic mutation that ... > full story
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