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Genetic Sequencing Could Help Match Patients With Biomarker-Driven Cancer Trials, Treatments
November 30, 2011 — A pilot study shows genetic sequencing could help match patients with biomarker-driven cancer ... > full story -
The Newest of the New in Gene Therapy: 'Tag and Target and Exchange'
November 30, 2011 — New research demonstrates how a combination of two techniques improves the efficiency of experimental gene therapies, while reducing side effects. Scientists combined techniques involving ... > full story -
Future Prostate Cancer Treatments Might Be Guided by Math
November 21, 2011 — Scientists have designed a first draft of a mathematical model that someday could guide treatment decisions for advanced prostate cancer, in part by helping doctors predict how individual patients ... > full story -
Genetic Rearrangements Drive 5 to 7 Percent of Breast Cancers
November 20, 2011 — Researchers have discovered two cancer-spurring gene rearrangements that may trigger 5 to 7 percent of all breast ... > full story -
Old Drugs Find New Target for Treating Brain Tumor
November 18, 2011 — Scientists say they have identified a novel gene mutation that causes at least one form of glioblastoma, the most common type of malignant brain ... > full story -
Signaling Pathway Linked to Inflammatory Breast Cancer May Drive Disease Metastasis
November 13, 2011 — Amplification of anaplastic lymphoma kinase, which has been reported in other cancers such as non-small cell lung cancers, may be a primary driver of the rapid metastasis that patients with ... > full story -
Benefit of Novel Drug in Breast Cancer Seen in Blood Within Weeks
November 13, 2011 — Clinical benefit from use of a novel histone deacetylase inhibitor drug may be determined by examining blood cells days after a patient receives treatment. The drug, entinostat, is the first histone ... > full story -
Tailored Therapy for Anti-Platelet Drugs Using a Novel Point-of-Care Genetic Test Provides Improved Response to Medications Compared to Current Standard of Care
November 9, 2011 — A clinical trial of patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) and stable angina showed that a strategy of rapid genotyping followed by selective ... > full story -
Metabolic Protein Plays Unexpected Role in Tumor Cell Formation and Growth
November 6, 2011 — The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers. Now, researchers report that PKM2 has important non-metabolic ... > full story -
Gene Responsible for Relapses in Young Leukemia Patients
October 26, 2011 — One of the causes of resistance to cancer treatment in children is now beginning to be elucidated. Acute lymphoblastic leukemia patients with a particular form of the ATF5 gene are at higher risk of ... > full story
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