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Genes Found Linked to Breast Cancer Drug Resistance Could Guide Future Treatment Choices
January 24, 2010 — Researchers have discovered a gene activity signature that predicts a high risk of cancer recurrence in certain breast tumors that have been treated with commonly used chemotherapy drugs. The ... > full story -
A Role for the Protein C-Myb in Leukemia
January 19, 2010 — Our genes are arranged on 23 pairs of chromosomes. Chromosomal abnormalities that occur when nonmatching pairs of chromosomes swap genetic information are known as chromosomal translocations. ... > full story -
Cancer Genome Atlas Identifies Distinct Subtypes of Deadly Brain Cancer
January 19, 2010 — The most common form of malignant brain cancer in adults, glioblastoma multiforme (GBM), is not a single disease but appears to be four distinct molecular subtypes, according to a study by the Cancer ... > full story -
Informative Method to Identify Biomarkers for Guiding Therapy Decisions
January 14, 2010 — A randomized biomarker-stratified design, which uses the biomarker to guide analysis but not treatment assignment, provides a rigorous assessment of the utility of a potential biomarker for guiding ... > full story -
Personalized Medicine
Viruses
Wounds and Healing
Multiple Sclerosis Research
Gene Therapy
Infectious Diseases
Novel and Simple Formula to Predict Treatment Success in Chronic Hepatitis C
January 14, 2010 — A study group from Japan used only simple clinical data to predict the treatment success of peg-interferon plus ribavirin therapy for chronic hepatitis C with a formula using a logistic regression ... > full story -
Muscular Dystrophy
Heart Disease
Diseases and Conditions
Birth Defects
Personalized Medicine
Today's Healthcare
Gene Mutations in Patients With Becker Muscular Dystrophy Identified
January 13, 2010 — Researchers have identified a link between specific modifications of the dystrophin gene and the age of cardiac disease onset in patients with Becker muscular dystrophy (BMD). This information could ... > full story -
EGFR Gene Signature Predicts Non-Small Cell Lung Cancer Prognosis
January 12, 2010 — Epidermal growth factor receptor (EGFR) is a validated therapeutic target for non-small cell lung cancer. Researchers have now discovered a 93-gene signature that is associated with the presence of ... > full story -
Gene Testing Identifies Lung Cancer Patients Who Benefit from ALK-Inhibitor Drug
January 12, 2010 — Results of a new study in non-small cell lung cancer showed that patients with specific oncogenic rearrangements of the anaplastic lymphoma kinase (ALK) gene within the short arm of chromosome 2 of ... > full story -
Breast Cancer Multigene Test Helping Patients Avoid Chemotherapy
January 11, 2010 — A 21-gene test that predicts whether early stage breast cancer patients will benefit from chemotherapy is having a big impact on treatment decisions by patients and doctors alike, according to a new ... > full story -
Genetic Differences Between Lethal and Treatable Forms of Leukemia Discovered
January 7, 2010 — A tumor's genetic profile is often useful when diagnosing and deciding on treatment for certain cancers, but inexplicably, genetically similar leukemias in different patients do not always respond ... > full story
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