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How to Make Preclinical Animal Research More Effective
July 23, 2013 — Only 11% of drugs that enter clinical trials in humans are ultimately found safe and effective enough to receive regulatory approval. One possible reason for this dismal success rate is flawed ... > full story -
Natural Pest Control Protein Effective Against Hookworm: A Billion Could Benefit
July 23, 2013 — A benign crystal protein, produced naturally by bacteria and used as an organic pesticide, could be a safe, inexpensive treatment for parasitic worms in humans and provide effective relief to over a ... > full story -
Chemical Reaction Could Streamline Manufacture of Pharmaceuticals and Other Compounds
July 22, 2013 — Researchers have discovered a new chemical reaction that has the potential to lower the cost and streamline the manufacture of compounds ranging from agricultural chemicals to pharmaceutical drugs. ... > full story -
New Hope for Hormone Resistant Breast Cancer
July 22, 2013 — A new finding provides fresh hope for the millions of women worldwide with estrogen receptor positive breast cancer. Scientists have shown that a specific change, which occurs when tumors become ... > full story -
New Plan of Attack in Cancer Fight: Two-Drug Combination, Under Certain Circumstances, Can Eliminate Disease
July 19, 2013 — New research shows that, under certain conditions, using two drugs in a "targeted therapy" -- a treatment approach designed to interrupt cancer's ability to grow and spread -- nearly all cancers ... > full story -
Weight Loss Drug Helps Curb Cocaine Addictions
July 18, 2013 — The drug topiramate, typically used to treat epilepsy and more recently weight loss, may also help people addicted to both cocaine and alcohol use less cocaine, particularly heavy users, researchers ... > full story -
Drug Research: New Technique Shows If Drugs Have Reached Intended Target
July 18, 2013 — The search for new drugs, including those for cancer, is set to speed up thanks to a new research technique which could tell if drugs had reached their intended ... > full story -
Compounds Outsmart Solid Tumors' Malfunctioning Machinery
July 17, 2013 — Molecular biologists have found a novel way to fine-tune the activity of cells' protein-disposing machinery, with potentially cancer-fighting ... > full story -
Compound Discovered at Sea Shows Potency Against Anthrax
July 17, 2013 — Scientists have discovered anthracimycin, a new chemical compound from an ocean microbe that could one day set the stage for new treatments for anthrax and other ailments such as ... > full story -
Nano Drug Crosses Blood-Brain Tumor Barrier, Targets Brain-Tumor Cells and Blood Vessels
July 17, 2013 — The blood-brain barrier protects the brain from poisons but also prevents drugs from reaching brain tumors. A preclinical study shows that an experimental nanotechnology drug called SapC-DOPS crosses ... > full story
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