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Teamwork Between Two Key Proteins Necessary For Normal Development And Regulation Of Red Blood Cells
August 6, 2007 — Researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for ... > full story -
Pathway That Eliminates Genetic Defects In Red Blood Cells Discovered
August 1, 2007 — Researchers have discovered a unique molecular pathway that detects and selectively eliminates defective messenger RNAs from red blood cells. Knowing how this specific surveillance system works can ... > full story -
Red Cell Substitute Shows Promise As Treatment For Sickle Cell Disease
July 27, 2007 — Studies in mice suggest that a red blood cell substitute based on human hemoglobin could be a promising new treatment for sickle cell disease in humans. Researchers report on experiments in mice ... > full story -
Network Model Predicts Risk Of Death In Sickle Cell Disease
July 11, 2007 — Researchers have developed a method to estimate sickle cell disease severity and predict the risk of death in people with this disease. The reliability of the model was supported by analysis of two ... > full story -
Sleeping Beauty 'Jumping Gene' Shows Promise For Sickle Cell Gene Therapy
June 5, 2007 — The Sleeping Beauty tranposon (SB-Tn) system, a gene therapy technology that avoids the pitfalls of transferring genes with viruses, shows promise in laboratory experiments for correcting the gene ... > full story -
Serious Illness Among Children With Sickle Cell Disease Reduced With Vaccine
May 1, 2007 — A vaccine introduced in 2000 has reduced by more than 90 percent the rate of a serious bacterial illness among young children with sickle cell disease (SCD), who are particularly susceptible to it, ... > full story -
Novel Gene-Repair Technology Under Development
April 26, 2007 — A new biotechnology company founded by University of Delaware researchers, is developing technologies for repairing genes that cause rare, hereditary diseases such as sickle cell anemia and spinal ... > full story -
How Blood Cells Change Shape
March 21, 2007 — Millions of times during their four-month lifespan, human red blood cells must squeeze through tiny capillaries to deliver their payload of oxygen and pick up waste carbon dioxide-functions essential ... > full story -
NIST 'Micro-Rack' Measures Cell Mechanical Properties
March 2, 2007 — Researchers at NIST have developed a microelectromechanical system (MEMS) cell-stretcher that can measure the mechanical properties of a living cell, such as its ability to stick to a surface. The ... > full story -
New Imaging Technique Tracks Traffic Patterns Of White Blood Cells
February 27, 2007 — Researchers at Mount Sinai School of Medicine have just developed an advanced imaging technique to capture the movement of the microdomains of leukocytes or white blood ... > full story
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