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Novel Way To Remove Iron From Ferritin Could Dramatically Improve Sickle Cell Treatment
November 2, 2007 A small protein or heptapeptide could be used to accelerate the removal of iron from ferritin, according to new research. The results of this study may help scientists develop new medications that ... > full story -
Anticlotting Drug Found To Be Safe In Sickle Cell Patients, Study Suggests
October 11, 2007 An intravenous "blood thinner" widely used in patients with acute coronary syndromes and during coronary artery stent placement appears to be safe in patients with sickle cell disease and may have ... > full story -
Teamwork Between Two Key Proteins Necessary For Normal Development And Regulation Of Red Blood Cells
August 6, 2007 Researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for ... > full story -
Pathway That Eliminates Genetic Defects In Red Blood Cells Discovered
August 1, 2007 Researchers have discovered a unique molecular pathway that detects and selectively eliminates defective messenger RNAs from red blood cells. Knowing how this specific surveillance system works can ... > full story -
Red Cell Substitute Shows Promise As Treatment For Sickle Cell Disease
July 27, 2007 Studies in mice suggest that a red blood cell substitute based on human hemoglobin could be a promising new treatment for sickle cell disease in humans. Researchers report on experiments in mice ... > full story -
Network Model Predicts Risk Of Death In Sickle Cell Disease
July 11, 2007 Researchers have developed a method to estimate sickle cell disease severity and predict the risk of death in people with this disease. The reliability of the model was supported by analysis of two ... > full story -
Sleeping Beauty 'Jumping Gene' Shows Promise For Sickle Cell Gene Therapy
June 5, 2007 The Sleeping Beauty tranposon (SB-Tn) system, a gene therapy technology that avoids the pitfalls of transferring genes with viruses, shows promise in laboratory experiments for correcting the gene ... > full story -
Serious Illness Among Children With Sickle Cell Disease Reduced With Vaccine
May 1, 2007 A vaccine introduced in 2000 has reduced by more than 90 percent the rate of a serious bacterial illness among young children with sickle cell disease (SCD), who are particularly susceptible to it, ... > full story -
Novel Gene-Repair Technology Under Development
April 26, 2007 A new biotechnology company founded by University of Delaware researchers, is developing technologies for repairing genes that cause rare, hereditary diseases such as sickle cell anemia and spinal ... > full story -
How Blood Cells Change Shape
March 21, 2007 Millions of times during their four-month lifespan, human red blood cells must squeeze through tiny capillaries to deliver their payload of oxygen and pick up waste carbon dioxide-functions essential ... > full story
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