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Researchers Model Fetal-to-Adult Hemoglobin Switching: Important Step Towards Cure for Blood Diseases
February 16, 2011 — Researchers have engineered mice that model the switch from fetal to adult hemoglobin, an important step towards curing genetic blood diseases such as sickle cell anemia and ... > full story -
Acute Anemia Linked to Silent Strokes in Children
February 11, 2011 — Silent strokes, which have no immediate symptoms but could cause long-term cognitive and learning deficits, occur in a significant number of severely anemic children, especially those with sickle ... > full story -
Compound May Prevent Sickle Cell Pain Crises
February 1, 2011 — A new compound appears to prevent the traffic jam of cells that causes debilitating pain crises and associated mortality in sickle cell disease, researchers ... > full story -
Two Studies Provide Insight Into Stroke Risk and Prevention in Young Sickle Cell Anemia Patients
December 6, 2010 — Monthly blood transfusions combined with daily medication to remove the resulting excess iron remains the best approach for reducing the risk of recurrent strokes in young patients with sickle cell ... > full story -
Studies Investigate Pediatric Sickle Cell Disease and Potential Breakthrough in Controlling Malaria
December 6, 2010 — New research highlights studies on transfusion therapy alternatives and genetic predictors for sickle cell-related stroke in children, the use of hydroxyurea therapy to reduce mortality in pediatric ... > full story -
Global Map of the Sickle Cell Gene Supports 'Malaria Hypothesis'
November 2, 2010 — At a global scale, the sickle cell gene is most commonly found in areas with historically high levels of malaria, adding geographical support to the hypothesis that the gene, while potentially ... > full story -
Inhaling Nitric Oxide Eases Pain Crises in Sickle Cell Patients, Researchers Find
October 19, 2010 — Inhaling nitric oxide appears to safely and effectively reduce pain crises in adults with sickle cell disease, researchers report. A study of 18 patients in Atlanta, Chicago and Detroit showed that ... > full story -
Shorter Biological Marker Length in Aplastic Anemia Patients Linked to Higher Relapse, Death Rates
September 21, 2010 — Among patients receiving immunosuppressive therapy for severe aplastic anemia (a condition in which the bone marrow is unable to produce blood cells), the length of telomeres (chromosome markers of ... > full story -
New Sickle Cell Screening Program for College Athletes Comes With Serious Pitfalls, Experts Say
September 8, 2010 — A leading pediatrician is urging a "rethink" of a new sickle cell screening program, calling it an enlightened but somewhat rushed step toward improving the health of young people who carry the ... > full story -
Evolution May Have Pushed Humans Toward Greater Risk for Type 1 Diabetes
August 17, 2010 — Gene variants associated with an increased risk for type 1 diabetes and rheumatoid arthritis may confer previously unknown benefits to their human carriers, say researchers. As a result, the human ... > full story
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