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Combination of Targeted Treatment Drugs Delays Resistance in Melanoma Patients
September 29, 2012 — Combined treatment with two drugs targeting different points in the same growth-factor pathway delayed the development of treatment resistance in patients with BRAF-positive metastatic malignant ... > full story -
Trial Shows Effectiveness of Low-Cost Intervention to Improve Sun Protection
September 24, 2012 — A double-blind randomized clinical trial of mailed sun protection packets led to higher frequency of sun protective behaviors including the use of long clothing, hats, shade, sunscreen, and midday ... > full story -
Genetically-Engineered Preclinical Models Predict Pharmacodynamic Response
September 19, 2012 — A new comparison of four different methodologies for pharmacokinetic and pharmacodynamic testing of the anti-melanoma agent carboplatin, demonstrates that genetically-engineered mouse models provide ... > full story -
Fighting Melanoma's Attraction to the Brain
September 19, 2012 — A researcher is delving deeper into the way the brain attracts cancer cells, and his breakthrough is giving scientists new hope for better ... > full story -
Cause of Chemotherapy Resistance in Melanoma Found
September 17, 2012 — Researchers have identified a major reason why melanoma is largely resistant to chemotherapy. They found a genetic pathway in melanoma cells that inhibits the cellular mechanism for detecting DNA ... > full story -
Drug Combination Against NRSA-Mutant Melanoma Discovered
September 17, 2012 — Scientists have discovered a novel drug combination aimed at a subset of melanoma patients who currently have no effective therapeutic options. About one-fourth of melanoma patients have NRAS-mutant ... > full story -
Missing Pieces of DNA Structure Is a Red Flag for Deadly Skin Cancer
September 13, 2012 — Researchers have discovered a new biomarker for melanoma. The findings offer novel opportunities for skin cancer diagnostics, treatment and ... > full story -
Cloned Receptor Paves Way for New Breast and Prostate Cancer Treatment
September 13, 2012 — Researchers have cloned a T-cell receptor that binds to an antigen associated with prostate cancer and breast cancer. T cells that have been genetically equipped with this T-cell receptor have the ... > full story -
Technique Using Computed Tomography Associated With Improved Detection of Lymph Node Metastasis in Patients With Melanoma
September 11, 2012 — Preoperative 3-dimensional visualization of sentinel lymph nodes (SLNs) with a technique known as single-photon emission computed tomography/computed tomography was associated with a higher rate of ... > full story -
Melanoma Manifests Differently in Children Than in Adults, Study Finds
September 7, 2012 — Physicians studying melanoma and related conditions occurring in childhood recently published results of their experience with cases of pathologically confirmed childhood melanoma. They found ... > full story
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