Tuberculosis News
September 1, 2015

Latest Headlines
updated 11:52am EDT

More Tuberculosis News
September 1, 2015

Powering Off TB: New Electron Transport Gene Is a Potential Drug Target

Aug. 12, 2015 — The US Food and Drug Administration recently approved the first new drug to fight tuberculosis in more than 40 years, but treatment still takes six months, 200 pills and leaves 40 percent of patients ... read more

Novel Toxin, and the First Ever Found, for Deadly Pathogen M. Tuberculosis

Aug. 3, 2015 — The first known toxin of the pathogenic bacterium Mycobacterium tuberculosis has been described by scientists. This necrotizing toxin is the founding member of a novel class of previously ... read more

Pneumonia Investment Doesn't Match Mortality Burden

July 15, 2015 — UK investment in pneumonia research is lacking when compared to spending on influenza and tuberculosis, according to a new study. By calculating the amount spent on researching respiratory infections ... read more

Multidrug-Resistant TB Appears Less Transmissible in Households Than Drug-Susceptible TB

June 23, 2015 — Some strains of multidrug-resistant tuberculosis (MDRTB) may have a lower fitness (be less capable of spreading) than drug-susceptible tuberculosis bacteria, according to a new study. The study ... read more

June 4, 2015 — Scientists have discovered a new target for the fight against multi-resistant mycobacteria, from a rejuvenated antibiotic series. Mycobacterium tuberculosis is the main cause of tuberculosis. The ... read more

Testing for Tuberculosis Reliably and Quickly

May 28, 2015 — Researchers have developed a simple diagnostic test to quickly and reliably detect tuberculosis in ... read more

New Test Could Identify Resistant Tuberculosis Faster

May 13, 2015 — The time needed to genetically sequence the bacteria causing tuberculosis (Mtb) from patient samples has been reduced from weeks to days using a new technique. This could help health service ... read more

Unexpected Role for Calcium in Controlling Inflammation During Chronic Lung Infection

May 4, 2015 — Many of us take a healthy immune system for granted. But for certain infants with rare, inherited mutations of certain genes, severe infection and death are stark consequences of their impaired ... read more

Locally Sourced Drugs Can Be Effective for Treating Multidrug-Resistant TB

Apr. 29, 2015 — Locally sourced antibiotics can be as effective as 'internationally quality-assured' antibiotics for treating multidrug-resistant tuberculosis in Pakistan, and may help avoid delays in ... read more

Turning to Freshwater Sources to Fight Drug-Resistant Tuberculosis, Other Infections

Apr. 8, 2015 — The discovery of antibiotics produced by soil fungi and bacteria gave the world life-saving medicine. But new antimicrobials from this resource have become scarce as the threat of drug resistance ... read more

Mar. 30, 2015 — Researchers have identified blood-based biomarkers in patients with active tuberculosis that could lead to new blood-based diagnostics and tools for monitoring treatment response and cure. ... read more

How the Human Immune System Keeps TB at Bay

Mar. 26, 2015 — A new tissue culture model using human white blood cells shows how people with a latent -- or symptom-free -- tuberculosis infection are protected from active disease by a critical early step in ... read more

Xpert MTB/RIF Assay for Diagnosis of Pulmonary Tuberculosis in Children: A Systematic Review and Meta-Analysis

Mar. 24, 2015 — Microbiological confirmation of childhood tuberculosis is rare because of the difficulty of collection of specimens, low sensitivity of smear microscopy, and poor access to culture. A new study aimed ... read more

Mar. 23, 2015 — Scientists have for the first time used DNA sequencing to trace the fatal spread of multidrug-resistant tuberculosis between patients in the UK. TB is spread by inhaling tiny airborne droplets from ... read more

Phase 2b Trial Results of Novel TB Regimen Show Potential to Shorten Treatment

Mar. 18, 2015 — A new tuberculosis (TB) drug regimen designed to improve options for TB therapy eliminated more bacteria from sputum than standard therapy and did so at a faster rate, according to data from a phase ... read more

Mar. 16, 2015 — The largest genetic study of tuberculosis susceptibility to date has led to a potentially important new insight into how the pathogen manages to evade the immune system. The study advances ... read more

Key to Tuberculosis Resistance Found

Mar. 2, 2015 — The cascade of events leading to bacterial infection and the immune response is mostly understood. However, the molecular mechanisms underlying the immune response to the bacteria that causes ... read more

Feb. 24, 2015 — A new small molecule drug has been discovered that may serve as a treatment against multi-drug resistant tuberculosis, a form of the disease that cannot be cured with conventional therapies. While ... read more

Elucidating the Origin of MDR Tuberculosis Strains

Jan. 28, 2015 — A study has focused on the evolutionary history of the mycobacterium that causes tuberculosis, and more specifically on the Beijing lineage associated with the spread of multidrug resistant forms of ... read more

Shorter Combination Treatment as Effective as Monotherapy for TB Prevention in Kids

Jan. 12, 2015 — To prevent tuberculosis in children with latent tuberculosis infection (which is not active but can become active), combination treatment with the medications rifapentine and isoniazid was as ... read more

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