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Exploring New Therapy Strategies For Tuberculosis
Certain protein degradation
complexes, molecular
"shredders" dispose of
protein garbage. Molecular
machines of this kind have
now been successfully
... > full story
TB -- Hiding In Plain Sight
Current research suggests
that Mycobacterium
tuberculosis can evade the
immune response. The related
report by Rahman et al.,
"Compartmentalization of
immune responses in human
... > full story
TB Vaccine Enters New Clinical Trials
The world's leading
candidate for a tuberculosis
vaccine is to enter Phase
IIb proof-of-concept
clinical trials, making it
the first TB candidate
vaccine for more than 80
... > full story
Discovery Of Tuberculosis Bacterium Enzyme Paves Way For New TB Drugs
Scientists have paved the
way for the development of
new drug therapies to combat
active and asymptomatic
(latent) tuberculosis
... > full story
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Existing Parkinson's Disease Drug May Fight Drug-resistant TB
July 4, 2009 — Existing drugs used in the treatment of Parkinson's disease could be repositioned for use in the treatment of extreme drug-resistant tuberculosis, which kills about 2 million people each year, ... > full story -
Carb Synthesis Sheds Light On Promising Tuberculosis Drug Target
June 30, 2009 — A fundamental question about how sugar units are strung together into long carbohydrate chains has also pinpointed a promising way to target new medicines against ... > full story -
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Multiple Sclerosis Research
Measurements Fail To Identify TB Patients Who Could Benefit From Shorter Treatment Course
June 30, 2009 — Testing whether two simple clinical measurements might help identify which TB patients could benefit from shorter treatment, researchers report that these measurements failed to ... > full story -
Scientists Solve Mystery About Why HIV Patients Are More Susceptible To TB Infection
June 30, 2009 — Scientists took an important first-step toward the development of new treatments to help people with HIV battle Mycobacterium tuberculosis infection. HIV interferes with the cellular and molecular ... > full story -
Unexpected Discovery Can Open A New Chapter In The Fight Against Tuberculosis
June 9, 2009 — A close relative of the microorganism that causes tuberculosis in humans has been found to form spores. This discovery might constitute a new turn in the fight against human ... > full story -
Infection Control 'Urgently Needed' To Curb Spread Of XDR-TB Among Health Care Workers
May 19, 2009 — Health care workers in South Africa are at a significantly increased risk of developing drug-resistant tuberculosis, or XDR-TB, in a trend which threatens to further exacerbate the already ... > full story -
Public Health
Tuberculosis
Personalized Medicine
Today's Healthcare
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Diseases and Conditions
TB Screening Needs To Be Targeted For Maximum Public Health Benefit, Study Suggests
May 19, 2009 — New estimates of the likelihood that a latent case of tuberculosis will become active have resulted in a roughly 50 percent increase over previous estimates of the number of people needed to be ... > full story -
LXR Proteins: New Target In The War On Tuberculosis?
May 16, 2009 — New research has identified a role for LXR proteins in the mouse immune response to airway infection with the bacterium that causes tuberculosis. As treatment of normal mice with molecules that ... > full story -
Excluding The Lateral View In Chest Radiograph Screenings Decreases Radiation Exposure By 67 Percent
April 23, 2009 — For the patient with a positive PPD test, which usually indicates prior exposure to tuberculosis, the guidelines recommend a chest x-ray that typically includes a frontal and lateral view. The ... > full story -
Rifampin Kinetics Poor In Children, Study Suggests
April 21, 2009 — Rifampin, a first-line antituberculosis drug, reaches serum concentrations well below suggested lower limits when a standard dose of 8-12mg/kg body weight is given to children. A pharmacokinetic ... > full story
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