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New Dry Powder Antibiotic Targets Tuberculosis, Reduces Treatment Time
November 16, 2010 Scientists have developed an inhalable dry powder antibiotic that when used alone or with current treatments may significantly reduce treatment for tuberculosis (TB) and multi-drug resistant ... > full story -
Tuberculosis
Pharmacology
Pharmaceuticals
Infectious Diseases
Biotechnology
Biotechnology and Bioengineering
TB-Drugome Provides New Targets for Anti-Tuberculosis Drug Discovery
November 8, 2010 Researchers have linked hundreds of federally approved drugs to more than 1,000 proteins in Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), opening new avenues to repurpose ... > full story -
New Strategy to Kill Bugs -- Even Those in Hiding
October 26, 2010 New strategies to apply antibiotics more effectively to hibernating bugs have been developed by researchers in the ... > full story -
Key Difference in How TB Bacteria Degrade Doomed Proteins
October 17, 2010 Scientists have discovered a key difference in the way human cells and Mycobacterium tuberculosis bacteria, which cause TB, deliver unwanted proteins to their respective cellular recycling factories. ... > full story -
Computer Modeling
Biotechnology and Bioengineering
Tuberculosis
Bacteria
Computational Biology
Computers and Internet
New Tool in the Fight Against Tuberculosis: Algorithm Enables Cell-Scale Simulations
October 7, 2010 Researchers have developed a way to harness prodigious quantities of genomic and metabolic data by developing an algorithm that automatically integrates both data sets. The model, called ... > full story -
New TB Pathogen Discovered
September 30, 2010 In studies of banded mongoose in Botswana, researchers have discovered a novel tuberculosis species in the Mycobacterium tuberculosis complex. Unlike other species of tuberculosis, which typically ... > full story -
U.S. Vulnerable to Multidrug-Resistant TB Epidemic, Computer Model Shows
September 27, 2010 While the United States has made great progress in the prevention and treatment of tuberculosis, the nation has become more susceptible to potential epidemics of multidrug-resistant tuberculosis, or ... > full story -
Elderly Might Not Benefit from TB Vaccines in Development
September 20, 2010 Elderly people might not benefit from some of the tuberculosis vaccines currently in development, recent research suggests. Some vaccines under study are designed to activate a specific molecule that ... > full story -
Possible 'Persistence' Switch for Tuberculosis Found: Computer Model Finds Probable Genetic Mechanism for TB Dormancy
September 17, 2010 A model for the genetic "persistence" switch that toggles tuberculosis bacteria into a dormant state that resists antibiotics and immune system responses is described in a new study. An analysis of ... > full story -
Tuberculosis: How Mycobacteria Avoid Destruction Inside Human Cells
September 9, 2010 Researchers have identified ten factors that help Mycobacterium tuberculosis avoid destruction inside host cell phagosomes. Two of the genes identified by high-throughput visual screening of 11,000 ... > full story
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