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Studies of Mutated Protein in Lou Gehrig’s Disease Reveal New Paths for Drug Discovery
April 26, 2011 — Several genes have been linked to ALS, with one of the most recent called FUS. Two new studies examined FUS biology in yeast and found that defects in RNA biology may be central to how FUS ... > full story -
Mutant Prions Help Cells Foil Harmful Protein Misfolding
March 20, 2011 — Misfolded proteins are implicated in many incurable neurological diseases. A new and improved understanding of how naturally occurring variants keep proteins from bunching up and spreading provides ... > full story -
New Research Focuses on Prion Diseases
March 14, 2011 — New research may shed light on possible treatments for prion ... > full story -
Needle-in-a-Haystack Search Identifies Potential Brain Disease Drug
February 23, 2011 — Scientists who examined more than 10,000 chemical compounds during the last year in search of potential new drugs for a group of untreatable brain diseases, are reporting that one substance shows ... > full story -
How Disordered Proteins Spread from Cell to Cell, Potentially Spreading Disease
February 18, 2011 — Misfolded proteins can get into cells and form large aggregates by recruiting normal proteins. These aggregates are associated with neurodegenerative diseases. A new study finds that the protein ... > full story -
Unraveling How Prion Proteins Move Along Axons in the Brain
February 17, 2011 — Researchers have identified the motors that move non-infectious prion proteins -- found within many mammalian cells -- up and down long, neuronal transport pathways. Identifying normal movement ... > full story -
Prion Disease Spreads in Sheep Via Mother's Milk
January 19, 2011 — Transmission of prion brain diseases such as bovine spongiform enecephalopathy (BSE) -- also known as mad cow disease -- and human variant Creutzfeldt-Jakob disease (vCJD) is generally attributed to ... > full story -
Airborne Pathogens Can Induce Mad Cow Disease, New Findings Suggest
January 13, 2011 — Airborne prions are also infectious and can induce mad cow disease or Creutzfeldt-Jakob disorder, new findings suggest. Researchers recommend precautionary measures for scientific labs, ... > full story -
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New Drug Target for Prion Diseases, 'Mad Cow'
January 10, 2011 — Scientists have discovered that plasminogen, a protein used by the body to break up blood clots, speeds up the progress of prion diseases such as mad cow ... > full story -
Prions Mutate and Adapt to Host Environment
December 17, 2010 — Scientists have shown that prions, bits of infectious protein that can cause fatal neurodegenerative disease such as bovine spongiform encephalopathy (BSE) or "mad cow disease," have the ability to ... > full story
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