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Shutting Down DNA Construction: How Senescence Halts Growth of Potential Cancers
April 4, 2013 — How does oncogene-induced senescence work? Imagine the cell as a construction site where work continues as long as bricks (nucleotides) are available. When an oncogene is damaged, it is like hiring ... > full story -
Protein Maintains Order in the Nucleus
April 4, 2013 — Two meters of DNA are packed into the cell nucleus, presumably based on a strictly defined arrangement. Researchers have now succeeded in explaining a phenomenon, which was first observed 40 years ... > full story -
Scientists Have Unravelled a Mechanism Critical for Fungal Virulence
April 4, 2013 — Metallothioneins, proteins able to capture metal ions, play a major role in the virulence of Cryptococcus neoformans, a fungal pathogen which causes severe infections in immunodeficient and ... > full story -
Pathogen's Scissor-Like Enzyme Provides New Clues to Treatment of Infectious Disease
April 4, 2013 — Researchers report that a pathogen annually blamed for an estimated 90 million cases of food-borne illness defeats a host's immune response by using a fat-snipping enzyme to cut off cellular ... > full story -
Course of Cardiovascular Events More Predictable: A Protein Enables Risk Assessment
April 4, 2013 — Medical researchers have managed to predict the probability of a cardiovascular patient suffering a heart attack, stroke or arterial occlusion within three months. In the long-term, this knowledge ... > full story -
The Equine 'Adam' Lived Fairly Recently: Close Relationships Among Modern Stallions
April 4, 2013 — The analysis of DNA inherited from a single parent has provided valuable insights into the history of human and animal populations. However, until recently we had insufficient information to be ... > full story -
Stem Cells Fill Gaps in Bones
April 4, 2013 — For many patients the removal of several centimeters of bone from the lower leg following a serious injury or a tumor extraction is only the beginning of a long-lasting ordeal. Autologous stem cells ... > full story -
Researchers Uncover a Genetic Vulnerability of Lung Cancer to Lay the Foundation for New Drug Options
April 4, 2013 — Physician-researchers at UT Southwestern have identified a vulnerability of certain lung-cancer cells – a specific genetic weakness that can be exploited for new ... > full story -
Can Repurposed Cancer Drugs Counter Bioterror Threats?
April 3, 2013 — Scientists are investigating whether two cancer medications have the potential of protecting U.S. troops from biological agents that could be unleashed during an ... > full story -
Brain Cell Signal Network Genes Linked to Schizophrenia Risk in Families
April 3, 2013 — New genetic factors predisposing to schizophrenia have been uncovered in five families with several affected relatives. These gene variants weaken NMDA receptors. Found throughout the brain, NMDA ... > full story
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