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Immunotherapy Showed Promising Antileukemia Activity in Pediatric Patients
April 7, 2013 — Researchers using patients' own immune cells in an immunotherapy approach called "anti-CD19 chimeric antigen receptor (CAR) T-cell therapy," achieved responses in children whose acute lymphocytic ... > full story -
New Type of Experimental Drug Active in Platinum-Resistant Ovarian Cancers
April 7, 2013 — The antibody-drug conjugate DMUC5754A, a novel member of a relatively new class of drugs, showed activity in women with ovarian cancer, even those with hard-to-treat, platinum-resistant disease, in a ... > full story -
More Accurate Markers Identified for Detecting Response to Epigenetic Drugs for Myelodysplastic Syndromes
April 7, 2013 — Researchers have identified and validated two DNA methylation markers that could help physicians to more accurately determine a patient's response to epigenetic drugs for treatment of myelodysplastic ... > full story -
Screening Blood Samples for Cancer-Driving Mutations More Comprehensive Than Analyzing Traditional Tumor Biopsy
April 7, 2013 — Researchers using a tool called BEAMing technology, which can detect cancer-driving gene mutations in patients' blood samples, were able to identify oncogenic mutations associated with distinct ... > full story -
Vaccine Adjuvant Uses Host DNA to Boost Pathogen Recognition
April 5, 2013 — Aluminum salts, or alum, have been injected into billions of people as an adjuvant to make vaccines more effective. No one knows, however, how they boost the immune response. Researchers continue ... > full story -
Researchers Help Unlock Pine Beetle's Pandora's Box
April 5, 2013 — A paper detailing the newly created sequencing of the mountain pine beetle's genome will be gold in the hands of scientists trying to stem the beetle's invasion into eastern ... > full storyMore: -
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Liver Transplantation for Patients With Genetic Liver Conditions Has High Survival Rate, Study Finds
April 5, 2013 — Patients faced with the diagnosis of a life-threatening liver disease have to consider the seriousness of having a liver transplant, which can be a definitive cure for many acquired and genetic liver ... > full story -
Researchers Identify Edema Inhibitor: Substance That Can Prevent the Accumulation of Fluid in Body Tissue
April 5, 2013 — Researchers in Germany have detected a substance that can prevent the accumulation of fluid in body tissue and thus edema formation. Their results could be important in the future for the treatment ... > full story -
Penn Medicine's New Center for Personalized Diagnostics Unlocks Cancer's Secrets
April 5, 2013 — Penn Medicine’s new Center for Personalized Diagnostics, a joint initiative of the department of Pathology and Laboratory Medicine in the Perelman School of Medicine and the Abramson Cancer ... > full story -
Cancer Checkpoint: Mitochondrial Metabolic Regulator SIRT4 Guards Against DNA Damage
April 5, 2013 — Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them. Researchers studying a set ... > full story
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