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Human Methylome Sequenced at Single Base-Pair Resolution
November 9, 2010 DNA methylation plays an important role in many processes such as animal development, X-chromosome inactivation, and carcinogenesis. Understanding the mechanisms and functions of DNA methylation and ... > full story -
Mystery Solved: How Genes Are Selectively Silenced
October 18, 2010 Cells read only those genes which are needed at a given moment, while the others are chemically labeled and, thus, selectively turned off. Scientists have now discovered how these labels are placed ... > full story -
On the Trail of the Epigenetic Code: Test System on Drosophila Should Provide the Key to Histone Function
October 11, 2010 Test system on fruit flies should provide the key to histone function. The genetic inherited material DNA was long viewed as the sole bearer of hereditary information. The function of its packaging ... > full story -
Cancer-Linked Epigenetic Effects of Smoking Found
October 9, 2010 For the first time, scientists have reported direct evidence that taking up smoking results in epigenetic changes associated with the development of ... > full story -
What Makes Us Age? Ticking of Cellular Clock Promotes Seismic Changes in Chromatin Landscape Associated With Aging
October 3, 2010 Like cats, human cells have a finite number of lives: once they divide a certain number of times (thankfully, more than nine) they change shape, slow their pace, and eventually stop dividing -- a ... > full story -
Epigenomics Discovery Yields New Information About Fat Cells
September 30, 2010 By creating a "map" of histone modifications in fat cells, investigators have discovered two new factors that regulate fat formation, a key step on the road to better understanding obesity, diabetes ... > full story -
Role of DNA Methylation in Multiple Myeloma Blood Cancer Identified
September 30, 2010 DNA methylation -- a modification of DNA linked to gene regulation -- is altered with increasing severity in a blood cancer called multiple myeloma, according to a new ... > full story -
At the Crossroads of Chromosomes: Study Reveals Structure of Cell Division’s Key Molecule
September 17, 2010 On average, one hundred billion cells in the human body divide over the course of a day. Most of the time the body gets it right but sometimes, problems in cell replication can lead to abnormalities ... > full story -
Genes Related to Body Mass Discovered
September 15, 2010 Scientists who specialize in unconventional hunts for genetic information outside nuclear DNA sequences have bagged a weighty quarry -- 13 genes linked to human body mass. The experiments screened ... > full story -
Genes Tied to Deadliest Ovarian Cancers Identified
September 8, 2010 Scientists have identified two genes whose mutations appear to be linked to ovarian clear cell carcinoma, one of the most aggressive forms of ovarian cancer. Clear cell carcinoma is generally ... > full story
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