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Smoking-Related Colorectal Cancer in Older Women Is Associated With Molecularly Defined DNA Changes
June 29, 2010 Smoking, an established risk factor for colon cancer, may induce specific epigenetic changes and gene mutations that may be involved in the development of colon cancer, according to a new ... > full story -
How Embryos Fight Retroviral Infection
June 24, 2010 Some viruses insert themselves into the host's DNA during infection in a process called retroviral integration, causing several diseases, including AIDS and cancer, notes a researcher who specializes ... > full story -
Certain Proteins Extend Life Span in Worms by 30 Percent
June 16, 2010 Researchers have identified a new group of proteins involved in determining the life span of laboratory roundworms. Blocking the expression of one member of the group can extend the worm's life span ... > full story -
Epigenetic Gene Silencing May Hold Key to Fatal Lung Vascular Disease
June 7, 2010 A rare but fatal disease of blood vessels in the lung may be caused in part by aberrant silencing of genes rather than genetic mutation. Pulmonary arterial hypertension has been linked to genetic ... > full story -
Epigenetic Similarities Between Wilms Tumor Cells and Normal Kidney Stem Cells Found
June 3, 2010 A detailed analysis of the epigenetics -- factors controlling when and in what tissues genes are expressed -- of Wilms tumor reveals striking similarities to stem cells normally found in fetal ... > full story -
Fatty Acid to Enhance Anticancer Drug
May 7, 2010 Scientists in Germany have discovered that bioavailability and efficacy of the blood cancer drug azacytidine increase when the substance is coupled to a fatty ... > full story -
Same Disease, Different Stem Cell Models
May 6, 2010 In the last three years, a new technique for reprogramming adult cells has given scientists an easier and less controversial way to harness the power of embryonic-like stem cells to study human ... > full story -
Pluripotent and Differentiated Human Cells Reside in Decidedly Different Epigenomic Landscapes
May 6, 2010 Human embryonic stem cells possess remarkable properties of self-renewal and pluripotency, the ability to become almost any kind of cell within the body. And yet they share the same genome or set of ... > full story -
Trauma-Induced Changes to Genes May Lead to Post-Traumatic Stress Disorder
May 4, 2010 Traumatic experiences "biologically embed" themselves in select genes, altering their functions and leading to the development of post-traumatic stress disorder, new research ... > full story -
'Epigenetic' Concepts Offer New Approach to Degenerative Disease
April 28, 2010 In studies on cancer, heart disease, neurological disorders and other degenerative conditions, some scientists are moving away from the "nature-versus-nurture" debate and are finding you're not a ... > full story
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