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Epigenetic Signals Differ Across Alleles
February 12, 2010 — Researchers have identified numerous novel regions of the genome where the chemical modifications involved in controlling gene expression are influenced by either genetic variation or the parental ... > full story -
Predicting Prognosis and Treatment Response in a Subset of Pancreatic Cancer Patients
February 11, 2010 — Specific chemical modifications to proteins called histones, which are found in the nucleus of cells and act as spools around which DNA is wound, can be used to predict prognosis and response to ... > full story -
New Insight Into Reprogramming of Cell Fate
January 27, 2010 — A discovery brings new insight into how cells are reprogrammed and a greater understanding of how the environment, or factors like nutritional signals, can interact with our genes to affect health. ... > full story -
Discovery of Epigenetic Memory During Breast Cancer
January 25, 2010 — Researchers have determined how the TGFB-Smad signaling pathway, which is over activated in late-stage cancers, is responsible for the "epigenetic memory" that maintains unique patterns of regulatory ... > full story -
Loss of Epigenetic Regulators Causes Mental Retardation
January 14, 2010 — Developing neurons don't just need the right genes to guide them as they grow, they need access to the right genes at the right times. The improper functioning of one specific protein complex that ... > full story -
New Mechanism Underlying Cocaine Addiction Discovered
January 7, 2010 — Researchers have identified a key epigenetic mechanism in the brain that helps explain cocaine's ... > full story -
Genetic Differences Between Lethal and Treatable Forms of Leukemia Discovered
January 7, 2010 — A tumor's genetic profile is often useful when diagnosing and deciding on treatment for certain cancers, but inexplicably, genetically similar leukemias in different patients do not always respond ... > full story -
Protein Complex Possibly Crucial for Triggering Embryo Development Identified
January 6, 2010 — Researchers have discovered a protein complex that appears to play a significant role in erasing epigenetic instructions on sperm DNA, essentially creating a blank slate for the different cell types ... > full story -
Epigenetics: Protein Linked to Leukemia 'Bookmarks' Highly Active Genes During Cell Division
January 5, 2010 — Scientists have discovered how some epigenetic instructions get stably transferred from one generation of cells to the next. They report that newly formed cells learn which genes need to become ... > full story -
Acute Stress Leaves Epigenetic Marks on the Hippocampus
December 31, 2009 — In trying to explain psychiatric disorders, genes simply cannot tell the whole story. The real answers are in the interaction of genes and the environment. Post-traumatic stress disorder requires ... > full story
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