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Epigenetic Control of Cardiogenesis
January 29, 2013 — Scientists have now been able to demonstrate that non-coding RNA is essential for normal embryonic ... > full story -
Jet Fuel, Plastics Exposures Cause Disease in Later Generations; Reproductive Diseases, Obesity
January 24, 2013 — Researchers have lengthened their list of environmental toxicants that can negatively affect as many as three generations of an exposed animal's offspring. Among them: BPA and jet fuel. And they see ... > full story -
Scientists Discover How Epigenetic Information Could Be Inherited: Mechanism of Epigenetic Reprogramming Revealed
January 24, 2013 — New research reveals a potential way for how parents' experiences could be passed to their offspring's ... > full story -
Personal Epigenetic 'Signatures' Found Consistent in Prostate Cancer Patients' Metastases
January 23, 2013 — In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic “signatures” across all metastatic tumors in ... > full story -
Epigenomic Abnormalities Predict Patient Survival in Non-Hodgkins Lymphoma
January 10, 2013 — "Not only do we see more abnormal methylation in non-Hodgkin lymphoma patients than in healthy B-cell populations, but there are three distinct subtypes of the disease in the clinic, each more ... > full story -
Cancer Scientists Determine Mechanism of One of the Most Powerful Tumor-Suppressor Proteins, Chd5
January 10, 2013 — Researchers have solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, Chd5, exerts its beneficial effects. Chd5 engages processes fundamental to cancer ... > full story -
Dimmer Switch for Regulating Cell's Read of DNA Code
January 9, 2013 — Researchers have been studying the epigenetics enzyme HDAC3 for several years. They discovered that its activity requires interaction with a specific region on another protein called the Deacetylase ... > full story -
In Epigenomics, Location Is Everything: Researchers Exploit Gene Position to Test 'Histone Code'
January 3, 2013 — In a novel use of gene knockout technology, researchers tested the same gene inserted into 90 different locations in a yeast chromosome -- and discovered that while the inserted gene never altered ... > full story -
New Insight Into Cell Development and Cancer
December 27, 2012 — New research has shed new light on how epigenetic signals may function together to determine the ultimate fate of a stem cell. The study implicates a unique class of proteins called polycomb-like ... > full story -
Cancer Study Overturns Current Thinking About Gene Activation
December 18, 2012 — A new Australian study shows that large regions of the genome -- amounting to roughly 2 percent -- are epigenetically activated in prostate cancer. Regions activated contain many prostate ... > full story
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