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Gene That Causes Newborn Spleen Disease Identified
April 11, 2013 — Researchers have identified the defective gene responsible for a rare disorder in which children are born without a spleen, which makes them susceptible to life-threatening bacterial infections. The ... > full story -
Blocking Immune Response Protein Helps Body Clear Chronic Infection; Potential Therapy for HIV, Other Viral Infections?
April 11, 2013 — Scientists have shown that temporarily blocking a protein critical to immune response actually helps the body clear itself of chronic infection. The finding suggests new approaches to treating HIV ... > full story -
Healing by the Clock: In Fruit Flies, Intestinal Stem-Cell Regeneration Fluctuates With the Time of Day
April 11, 2013 — Genetic screening in flies reveals that the circadian clock regulates intestinal regeneration in response to damage, meaning that gut healing fluctuates according to the time of ... > full story -
Cell-Destroyer That Fights and Promotes TB Reveals What's Behind Its Split Identity
April 11, 2013 — TB can be a disease not only of failed immunity but also of excessive immune response. Tumor necrosis factor -- normally an infection-fighting substance produced by the body -- can actually heighten ... > full story -
Mutations Found in Individuals With Autism Interfere With Endocannabinoid Signaling in the Brain
April 11, 2013 — Mutations found in individuals with autism block the action of molecules made by the brain that act on the same receptors that marijuana's active chemical acts on, according to new research. The ... > full story -
How Alzheimer's Could Occur: Wrong Signal for Cell Division?
April 11, 2013 — A new hypothesis has been developed on how Alzheimer's disease could occur. Protein spheres in the nucleus give the wrong signal for cell division. This may explain the degeneration and death of ... > full story -
Unusual Suspect: Scientists Find 'Second Fiddle' Protein Has Leading Role in Type 2 Diabetes
April 11, 2013 — Researchers have found that a protein long believed to have a minor role in type 2 diabetes is, in fact, a central player in the development of the condition that affects nearly 26 million people in ... > full story -
Genetic Master Controls Expose Cancers' Achilles' Heel
April 11, 2013 — In a surprising finding that helps explain fundamental behaviors of normal and diseased cells, scientists have discovered a set of powerful gene regulators dubbed “super-enhancers” that ... > full story -
New Protein Target for Controlling Diabetes
April 11, 2013 — Researchers have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release insulin. The discovery suggests a ... > full story -
Do Drugs for Bipolar Disorder 'Normalize' Brain Gene Function?
April 11, 2013 — Every day, millions of people with bipolar disorder take medicines to stabilize their moods. But just how these drugs work is still a mystery. Now, a new study of brain tissue helps reveal what might ... > full story
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