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Brain Disease 'Resistance Gene' Evolves in Papua New Guinea Community; Could Offer Insights Into CJD
November 20, 2009 A community in Papua New Guinea that suffered a major epidemic of a CJD-like fatal brain disease called kuru has developed strong genetic resistance to the disease, according to new research by ... > full story -
Researchers Find New Piece of Bovine Spongiform Encephalopathy (BSE) Puzzle
November 19, 2009 A new treatment route for bovine spongiform encephalopathy (BSE) and its human form Creutzfeldt Jakob disease could be a step closer based on new results from scientists in the UK. The team has found ... > full story -
Protein Srebp2 Drives Cholesterol Formation in Prion-Infected Neuronal Cells
November 18, 2009 The regulating protein Srebp2 drives cholesterol formation, which prions need for their propagation, in prion-infected neuronal cells. Scientists anticipate new approaches in drug development to ... > full story -
Cell Study Explains Why Younger People More at Risk of Variant Creutzfeldt-Jakob Disease (vCJD)
October 14, 2009 Specific cells within the immune system could help explain why younger people are more susceptible to variant Creutzfeldt-Jakob disease -- a rare, degenerative, fatal brain disorder. Patients ... > full story -
First Direct Information About Prion's Molecular Structure Reported
October 5, 2009 Scientists have discovered the first direct information about the molecular structure of prions. In addition, the study has revealed surprisingly large structural differences between natural prions ... > full story -
Evolutionary Origins Of Prion Disease Gene Uncovered
September 28, 2009 Scientists have uncovered the evolutionary ancestry of the prion gene, which may reveal new understandings of how the prion protein causes diseases such as bovine spongiform encephalopathy, also ... > full story -
Can Gene Expression Profiling Make It Possible To Predict Deadly Infections In Cattle?
September 10, 2009 A new study suggests that gene expression profiling may allow researchers to track the progression of bovine spongiform encephalopathy (BSE) in cattle and ultimately predict their infectious ... > full story -
Gene Mutation Alone Causes Transmissible Prion Disease
August 26, 2009 Researchers have shown definitively that mutations associated with prion diseases are sufficient to cause a transmissible neurodegenerative disease. Until now, two theories about the role mutations ... > full story -
Impaired Transport In Neurons Triggers Prion Disease
August 21, 2009 A new study shows that nervous system integrity and axonal properties may play a key role in prion diseases. The findings expand our understanding of the development of prion disease and suggest ... > full story -
Prion Protein Identified As Novel Early Pancreatic Cancer Biomarker
August 17, 2009 Mad cow disease is caused by the accumulation of an abnormal protein, the prion, in the brain of an affected patient. Outside of the brain, very little is known about prions. Researchers have, for ... > full story
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