Featured Research

from universities, journals, and other organizations

Semen Can Worsen Cervical Cancer

Date:
September 4, 2006
Source:
University Of Edinburgh
Summary:
Researchers from the Medical Research Council's Human Reproductive Sciences Unit at The University of Edinburgh have found that that the high concentration of prostaglandin in semen makes other diseases of the female reproductive organs worse -- including uterine cancer.

Researchers from the Medical Research Council's Human Reproductive Sciences Unit at The University of Edinburgh have found that that the high concentration of prostaglandin in semen makes other diseases of the female reproductive organs worse -- including uterine cancer.

The team, led by Dr Henry Jabbour, an Honorary Fellow in Obstetrics and Gynaecology at the University, has found the prostaglandins present in semen can influence the progression of cervical and uterine cancers by enhancing tumour growth.

Prostaglandin is naturally produced by the cells that line the female reproductive organs. Its usual role is to help regulate cell growth. For example, messages passed on from cell to cell by prostaglandin molecules direct the womb lining to either thicken or shed in the monthly menstrual cycle.

However, the concentration of prostaglandin in seminal fluid is 1000 times higher than that normally found in these cells.

Prostaglandin receptor molecules are present on the surface of the cells that make up cervical and uterine cancer tumours. The influx of prostaglandin delivered by semen enhances the normal level of signalling between cells. The high volume starts new cascades of signals that eventually lead to an increase in tumour growth.

Cervical cancer is most common in women who live in the developing world. In the UK, screening programmes detect most abnormal cell changes in women before a tumour develops. Although prostaglandins do not cause cervical cancer (it is usually triggered by long--term human papilloma virus infection), this research shows that seminal fluid can contribute to tumour growth.

Dr Henry Jabbour said:

"Sexually active women who are at risk of cervical or uterine cancer should encourage their partners to wear a condom to prevent increased exposure to the prostaglandins that might make their condition worse.

"It also highlights the potential for a new therapeutic approach that will tackle both possible sources of prostaglandin, those produced naturally by women and those introduced to the body by sperm."


Story Source:

The above story is based on materials provided by University Of Edinburgh. Note: Materials may be edited for content and length.


Cite This Page:

University Of Edinburgh. "Semen Can Worsen Cervical Cancer." ScienceDaily. ScienceDaily, 4 September 2006. <www.sciencedaily.com/releases/2006/09/060903151304.htm>.
University Of Edinburgh. (2006, September 4). Semen Can Worsen Cervical Cancer. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2006/09/060903151304.htm
University Of Edinburgh. "Semen Can Worsen Cervical Cancer." ScienceDaily. www.sciencedaily.com/releases/2006/09/060903151304.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Man Floats for 31 Hours in Gulf Waters

Man Floats for 31 Hours in Gulf Waters

AP (Sep. 16, 2014) A Texas man is lucky to be alive after he and three others floated for more than a day in the Gulf of Mexico when their boat sank during a fishing trip. (Sept. 16) Video provided by AP
Powered by NewsLook.com
Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

Ivorians Abandon Monkey Pets in Fear Over Ebola Virus

AFP (Sep. 16, 2014) Since the arrival of Ebola in Ivory Coast, Ivorians have been abandoning their pets, particularly monkeys, in the fear that they may transmit the virus. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com
Study Links Male-Pattern Baldness To Prostate Cancer

Study Links Male-Pattern Baldness To Prostate Cancer

Newsy (Sep. 16, 2014) New findings suggest men with a certain type of baldness at age 45 are 39 percent more likely to develop aggressive prostate cancer. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

    Environment News

      Technology News



      Save/Print:
      Share:

      Free Subscriptions


      Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

      Get Social & Mobile


      Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

      Have Feedback?


      Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
      Mobile: iPhone Android Web
      Follow: Facebook Twitter Google+
      Subscribe: RSS Feeds Email Newsletters
      Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins