Featured Research

from universities, journals, and other organizations

Link between vitamin D and basal cell carcinoma probed: Study sheds light on development of most common form of skin cancer

Date:
March 5, 2010
Source:
Henry Ford Health System
Summary:
A new has shown a link between Vitamin D levels and basal cell carcinoma, a finding that could lead researchers to better understand the development of the most common form of skin cancer. In a small study, researchers found elevated levels of Vitamin D enzymes and proteins in cancerous tissue taken from 10 patients compared to normal skin tissue taken from them.

A Henry Ford Hospital study has shown a link between Vitamin D levels and basal cell carcinoma, a finding that could lead researchers to better understand the development of the most common form of skin cancer.

Related Articles


In a small study, researchers at Henry Ford and Wayne State University found elevated levels of Vitamin D enzymes and proteins in cancerous tissue taken from 10 patients compared to normal skin tissue taken from them.

Previous studies have linked Vitamin D deficiency with certain cancers but this is believed to be the first time researchers looked at Vitamin D and basal cell carcinoma.

"This finding may help us in future research to determine whether vitamin D plays a causative or reactive role in the development and progression of skin cancer," says Iltefat Hamzavi, M.D., senior staff physician in Henry Ford's Department of Dermatology and the study's lead author.

The study will be presented at the Photomedicine Society's annual meeting in Miami, one day before the American Academy of Dermatology's annual meeting.

Basal cell carcinoma, which affects about 1 million Americans a year, is the most common form of skin cancer. This cancer forms in the basal cells of the deepest layer of the skin. Mohs micrographic surgery is one of the most effective treatments for removing skin cancer.

The 10 patients enrolled in the study were diagnosed with basal cell carcinoma and ranged in age from 43 to 83. All had biopsies taken of cancerous tissue and surrounding normal skin tissue. Researchers found a 10-fold increase in Vitamin D enzyme levels and a two-fold increase in Vitamin D protein levels. The enzymes and proteins help regulate levels of Vitamin D in the skin. Two genes that play a role in DNA and tumor repair also had elevated levels of Vitamin D in cancerous tissue compared to normal tissue.

The study was funded by the American Society of Dermatologic Surgery, Wayne State University and Henry Ford Hospital.


Story Source:

The above story is based on materials provided by Henry Ford Health System. Note: Materials may be edited for content and length.


Cite This Page:

Henry Ford Health System. "Link between vitamin D and basal cell carcinoma probed: Study sheds light on development of most common form of skin cancer." ScienceDaily. ScienceDaily, 5 March 2010. <www.sciencedaily.com/releases/2010/03/100304131609.htm>.
Henry Ford Health System. (2010, March 5). Link between vitamin D and basal cell carcinoma probed: Study sheds light on development of most common form of skin cancer. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/2010/03/100304131609.htm
Henry Ford Health System. "Link between vitamin D and basal cell carcinoma probed: Study sheds light on development of most common form of skin cancer." ScienceDaily. www.sciencedaily.com/releases/2010/03/100304131609.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins