Featured Research

from universities, journals, and other organizations

First-ever imaging of cells growing on spherical surfaces

Date:
September 21, 2012
Source:
Florida Institute of Technology
Summary:
The potential biomedical applications of the researchers' technique include new strategies and devices for the early detection and isolation of cancer cells, facilitating new methods of treating cancer tissues.

Shengyuan Yang, Florida Institute of Technology assistant professor of mechanical and aerospace engineering, with graduate student Sang Joo Lee, has published a paper on the first-ever imaging of cells growing on spherical surfaces. The paper is published in the online journal Review of Scientific Instruments, and will appear later in September in the print version.

The potential biomedical applications of the researchers' technique include new strategies and devices for the early detection and isolation of cancer cells, facilitating new methods of treating cancer tissues. "We also foresee new strategies and techniques to control the differentiation of stem cells and the morphologies and structures of the resulting cells and tissues," said Yang.

The effects of substrate stiffness on cell behaviors have been extensively studied; however, the effects of substrate curvature are not well-documented. The curvature of the surface on which cells adhere can have profound effects on cell behaviors, according to Yang.

"To reveal these cell mechano-biological responses to substrate curvatures, we have introduced a novel, simple, and flexible class of substrates, polyacrylamide gels embedded with micro glass balls ranging in diameter from 5 mm to 2 mm, to culture cells. To the best of our knowledge, this is the first experimental attempt to study cell responses to spherically-shaped substrates. Our cell culture experiments imply that this class of substrates, micro glass ball embedded gels, can be useful tools to study cell mechanobiological responses to substrate curvatures, related cell and tissue engineering researches, and biomedical applications, such as cancer detection and treatment, and the control of stem cell differentiations, for example," said Yang.

This work was supported with funding from the National Science Foundation (NSF) CAREER Program. The reviewer of this paper at Review of Scientific Instruments commented, according to Yang: "This is a clever idea. . . This work has great potentials with high impact."


Story Source:

The above story is based on materials provided by Florida Institute of Technology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Sang Joo Lee and Shengyuan Yang. Micro glass ball embedded gels to study cell mechanobiological responses to substrate curvatures. Review of Scientific Instruments, 2012; DOI: 10.1063/1.4751869

Cite This Page:

Florida Institute of Technology. "First-ever imaging of cells growing on spherical surfaces." ScienceDaily. ScienceDaily, 21 September 2012. <www.sciencedaily.com/releases/2012/09/120921162312.htm>.
Florida Institute of Technology. (2012, September 21). First-ever imaging of cells growing on spherical surfaces. ScienceDaily. Retrieved October 23, 2014 from www.sciencedaily.com/releases/2012/09/120921162312.htm
Florida Institute of Technology. "First-ever imaging of cells growing on spherical surfaces." ScienceDaily. www.sciencedaily.com/releases/2012/09/120921162312.htm (accessed October 23, 2014).

Share This



More Health & Medicine News

Thursday, October 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Orthodontist Mom Jennifer Salzer on the Best Time for Braces

Working Mother (Oct. 22, 2014) Is your child ready? Video provided by Working Mother
Powered by NewsLook.com
U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

U.S. Issues Ebola Travel Restrictions, Are Visa Bans Next?

Newsy (Oct. 22, 2014) Now that the U.S. is restricting travel from West Africa, some are dropping questions about a travel ban and instead asking about visa bans. Video provided by Newsy
Powered by NewsLook.com
US to Track Everyone Coming from Ebola Nations

US to Track Everyone Coming from Ebola Nations

AP (Oct. 22, 2014) Stepping up their vigilance against Ebola, federal authorities said Wednesday that everyone traveling into the US from Ebola-stricken nations will be monitored for symptoms for 21 days. (Oct. 22) Video provided by AP
Powered by NewsLook.com
Doctors Help Paralysed Man Walk Again, Patient in Disbelief

Doctors Help Paralysed Man Walk Again, Patient in Disbelief

AFP (Oct. 22, 2014) Polish doctors describe how they helped a paralysed man walk again, with the patient in disbelief at the return of sensation to his legs. Duration: 1:04 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins