Featured Research

from universities, journals, and other organizations

New tools for Alzheimer's may aid early diagnosis and treatment

Date:
October 15, 2012
Source:
Society for Neuroscience (SfN)
Summary:
Curtailing the imminent rise in Alzheimer's disease (AD) will require early, accurate diagnostic tests and treatments, and researchers are closer to achieving these two goals.

Curtailing the imminent rise in Alzheimer's disease (AD) will require early, accurate diagnostic tests and treatments, and researchers are closer to achieving these two goals.

New findings in medical imaging, molecular analysis of neurological diseases, and development of treatments using mouse models were presented at Neuroscience 2012, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

AD is the most common cause of dementia and currently affects 5 million people in the United States. By 2015, this number could increase to 13 million people.

Today's new findings show that:

  • Changes in brain function occur many years before symptoms in people with AD; these changes could be detected by PET scans and might one day be used to identify people at risk for developing the disease (Lori Beason-Held, PhD, abstract 545.22).
  • A new drug that targets biochemical changes in proteins improved symptoms and increased survival in a mouse model of AD, but just how it works is a mystery (Fred Van Leuven, PhD, abstract 416.08).
  • An antibody-based probe that uses nanotechnology and magnetic resonance imaging can distinguish between diseased and non-diseased brain tissue and could lead to a test for early detection of AD (William Klein, PhD, abstract 753.21).
  • AD, Parkinson's disease, and Dementia with Lewy Bodies have specific molecular signatures caused by epigenetics -- mechanisms that determine how and when DNA is expressed -- that could assist in accurate diagnosis and earlier treatment (Paula Desplats, PhD, abstract 50.17).
  • A new mouse model for AD gives researchers more control over an Alzheimer's-related protein in mice, and could lead to better research on effective treatments (Alena Savonenko, MD, PhD, abstract 416.04).

"Being able to detect AD early -- perhaps even before symptoms begin -- is an essential pre-condition if we are to develop effective treatments that slow or stop the changes that occur in the brain during Alzheimer's. Our studies in mice already tell us this," said press conference moderator Sam Gandy, PhD, MD, of the Mount Sinai School of Medicine in New York City, an expert on AD and dementia. "Being able to distinguish AD from other neurodegenerative diseases will help us give the right treatments to the right patients."


Story Source:

The above story is based on materials provided by Society for Neuroscience (SfN). Note: Materials may be edited for content and length.


Cite This Page:

Society for Neuroscience (SfN). "New tools for Alzheimer's may aid early diagnosis and treatment." ScienceDaily. ScienceDaily, 15 October 2012. <www.sciencedaily.com/releases/2012/10/121015112424.htm>.
Society for Neuroscience (SfN). (2012, October 15). New tools for Alzheimer's may aid early diagnosis and treatment. ScienceDaily. Retrieved April 23, 2014 from www.sciencedaily.com/releases/2012/10/121015112424.htm
Society for Neuroscience (SfN). "New tools for Alzheimer's may aid early diagnosis and treatment." ScienceDaily. www.sciencedaily.com/releases/2012/10/121015112424.htm (accessed April 23, 2014).

Share This



More Mind & Brain News

Wednesday, April 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Study Says Most Crime Not Linked To Mental Illness

Study Says Most Crime Not Linked To Mental Illness

Newsy (Apr. 22, 2014) A new study finds most crimes committed by people with mental illness are not caused by symptoms of their illness or disorder. Video provided by Newsy
Powered by NewsLook.com
How Smaller Plates And Cutlery Could Make You Feel Fuller

How Smaller Plates And Cutlery Could Make You Feel Fuller

Newsy (Apr. 22, 2014) NBC's "Today" conducted an experiment to see if changing the size of plates and utensils affects the amount individuals eat. Video provided by Newsy
Powered by NewsLook.com
Do We Get Nicer With Age?

Do We Get Nicer With Age?

Newsy (Apr. 22, 2014) A recent report claims personality can change over time as we age, and usually that means becoming nicer and more emotionally stable. Video provided by Newsy
Powered by NewsLook.com
How to Master Motherhood With the Best Work/Life Balance

How to Master Motherhood With the Best Work/Life Balance

TheStreet (Apr. 22, 2014) In the U.S., there are more than 11 million couples trying to conceive at any given time. From helping celebrity moms like Bethanny Frankel to ordinary soon-to-be-moms, TV personality and parenting expert, Rosie Pope, gives you the inside scoop on mastering motherhood. London-born entrepreneur Pope is the creative force behind Rosie Pope Maternity and MomPrep. She explains why being an entrepreneur offers the best life balance for her and tips for all types of moms. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins