Featured Research

from universities, journals, and other organizations

Depression risk factor for mortality in rheumatoid arthritis; men most at risk

Date:
November 11, 2012
Source:
American College of Rheumatology (ACR)
Summary:
Depression is higher in men and women with rheumatoid arthritis, and may increase mortality in this population, according to new research findings.

Depression is higher in men and women with rheumatoid arthritis, and may increase mortality in this population, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in Washington, D.C.

Related Articles


Rheumatoid arthritis is a chronic disease that causes pain, stiffness, swelling, limitation of motion and loss of function of multiple joints. Though joints are the principal areas affected by RA, inflammation can develop in other organs as well. An estimated 1.3 million Americans have RA, and the disease typically affects women twice as often as men.

Researchers used data collected from annual telephone surveys of 530 participants with RA who live in northern California to assess symptoms of depression and the potential impact of depression in this population. To qualify as depressed, participants must score greater than five on the Geriatric Depression Scale, a standardized measurement tool.

To be eligible, participants had to undergo an interview in either 2002 or 2003 with at least one follow-up interview. They were then followed until 2009. Participants' mean age was 60 with a mean disease duration of 19 years, and 84 percent were female. During the study, 63 participants died. Higher depression scores were associated with mortality in the study, said Patricia Katz, PhD, investigator in the study and professor of medicine and health policy at University of California, San Francisco.

"People with rheumatoid arthritis who were depressed were more likely to die than those with RA who were not depressed. We found that seemed to be particularly true for the men. The risk of death for depressed men was twice that for depressed women," says Dr. Katz.

Overall, men in this study had a higher mortality risk than women, after controlling for other variables. This was true for both depressed and non-depressed individuals; a baseline history of depression by the Geriatric Depression Scale resulted in approximately twice the mortality for both genders. When the increased risk associated with gender was combined with the risk associated with depression, men in the study whose scores indicated depression were five times as likely to die as women with RA whose scores indicated they were not depressed.

Men and women with increases in depressive symptoms, who may not have scored high enough on the Geriatric Depression Scale to be considered depressed, still had a higher mortality risk, says Dr. Katz. "An increase in the depressive symptom score, even if they didn't cross over that critical line to overt depression, was still associated with a higher level of mortality."

The study's findings suggest that depression and depressive symptoms are a significant risk factor for mortality in RA, although it is not necessarily a part of the disease process, says Dr. Katz.

"Patients need to be made aware that depression is something to pay attention to in RA, and they need to tell their physician about it. Rheumatologists and other health care providers need to be aware of the problem of depression in the clinical setting," Dr. Katz says.

Funding for this study was provided by the National Institute for Arthritis, Musculoskeletal, and Skin Diseases of the National Institutes of Health.


Story Source:

The above story is based on materials provided by American College of Rheumatology (ACR). Note: Materials may be edited for content and length.


Cite This Page:

American College of Rheumatology (ACR). "Depression risk factor for mortality in rheumatoid arthritis; men most at risk." ScienceDaily. ScienceDaily, 11 November 2012. <www.sciencedaily.com/releases/2012/11/121111153518.htm>.
American College of Rheumatology (ACR). (2012, November 11). Depression risk factor for mortality in rheumatoid arthritis; men most at risk. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2012/11/121111153518.htm
American College of Rheumatology (ACR). "Depression risk factor for mortality in rheumatoid arthritis; men most at risk." ScienceDaily. www.sciencedaily.com/releases/2012/11/121111153518.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Mind & Brain News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
Yoga Could Be As Beneficial For The Heart As Walking, Biking

Yoga Could Be As Beneficial For The Heart As Walking, Biking

Newsy (Dec. 17, 2014) Yoga can help your weight, blood pressure, cholesterol and heart just as much as biking and walking does, a new study suggests. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins