Featured Research

from universities, journals, and other organizations

Do antidepressants improve mood and/or lessen seizure frequency in patients with epilepsy?

Date:
December 3, 2012
Source:
American Epilepsy Society (AES)
Summary:
Epilepsy and depression are common co-morbidities. Concern for the potential of certain antidepressants to induce seizures has led to under-treating depression and anxiety disorders in epilepsy patients. Research suggests that antidepressants in normal dosage may have a positive impact on both mood and seizure frequency.

Epilepsy and depression are common co-morbidities. Concern for the potential of certain antidepressants to induce seizures has led to under-treating depression and anxiety disorders in epilepsy patients. Research presented today at the 66th American Epilepsy Society meeting suggests that antidepressants in normal dosage may have a positive impact on both mood and seizure frequency.

Related Articles


A research team at Rush University Medical Center, Chicago, conducted a retrospective study of 100 consecutive epilepsy patients started on selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). The purpose of the study was to establish the impact of these antidepressants on seizure frequency, and to determine whether an improvement in seizure frequency correlated with a decrease in depression and anxiety.(Platform C.05)

Changes in mood and anxiety data were obtained at three and six months. Excluded from the analysis were patients who had had anticonvulsant drug or procedure changes at the time of antidepressant introduction. Improvements and/or remission of symptoms were observed in 86% of patients who continued in the study.

According to lead investigator Ramses Ribot, M.D., "SSRIs and SNRIs do not appear to worsen seizure frequency and yield a good therapeutic response independently of seizure frequency. Our studies also suggest these antidepressants may actually have an anti-seizure effect in patients with frequent seizures."

The findings are potentially of broad interest to treating physicians. However, the researchers say their findings need to be confirmed in prospective double-blind placebo-controlled clinical trials.


Story Source:

The above story is based on materials provided by American Epilepsy Society (AES). Note: Materials may be edited for content and length.


Cite This Page:

American Epilepsy Society (AES). "Do antidepressants improve mood and/or lessen seizure frequency in patients with epilepsy?." ScienceDaily. ScienceDaily, 3 December 2012. <www.sciencedaily.com/releases/2012/12/121203121444.htm>.
American Epilepsy Society (AES). (2012, December 3). Do antidepressants improve mood and/or lessen seizure frequency in patients with epilepsy?. ScienceDaily. Retrieved March 4, 2015 from www.sciencedaily.com/releases/2012/12/121203121444.htm
American Epilepsy Society (AES). "Do antidepressants improve mood and/or lessen seizure frequency in patients with epilepsy?." ScienceDaily. www.sciencedaily.com/releases/2012/12/121203121444.htm (accessed March 4, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, March 4, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com
Mount Everest Has a Poop Problem

Mount Everest Has a Poop Problem

Buzz60 (Mar. 4, 2015) With no bathrooms to use, climbers of Mount Everest have been leaving human waste on the mountain for years, and it&apos;s becoming a health issue. Mike Janela (@mikejanela) has more. Video provided by Buzz60
Powered by NewsLook.com
Obamacare's New Supreme Court Battle

Obamacare's New Supreme Court Battle

Washington Post (Mar. 4, 2015) The Affordable Care Act is facing another challenge at the Supreme Court in King v. Burwell, which deals with subsidies for health insurance. The case could cut out a major provision of Obamacare, causing the law to unravel. Here’s what you need to know about the case. Video provided by Washington Post
Powered by NewsLook.com
Investigation Finds Hurt Workers Suffer More In Some States

Investigation Finds Hurt Workers Suffer More In Some States

Newsy (Mar. 4, 2015) ProPublica and NPR&apos;s joint investigation found drastic cuts to workers compensation benefits and employees&apos; access to those benefits. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins