Featured Research

from universities, journals, and other organizations

Do antidepressants improve mood and/or lessen seizure frequency in patients with epilepsy?

Date:
December 3, 2012
Source:
American Epilepsy Society (AES)
Summary:
Epilepsy and depression are common co-morbidities. Concern for the potential of certain antidepressants to induce seizures has led to under-treating depression and anxiety disorders in epilepsy patients. Research suggests that antidepressants in normal dosage may have a positive impact on both mood and seizure frequency.

Epilepsy and depression are common co-morbidities. Concern for the potential of certain antidepressants to induce seizures has led to under-treating depression and anxiety disorders in epilepsy patients. Research presented today at the 66th American Epilepsy Society meeting suggests that antidepressants in normal dosage may have a positive impact on both mood and seizure frequency.

Related Articles


A research team at Rush University Medical Center, Chicago, conducted a retrospective study of 100 consecutive epilepsy patients started on selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). The purpose of the study was to establish the impact of these antidepressants on seizure frequency, and to determine whether an improvement in seizure frequency correlated with a decrease in depression and anxiety.(Platform C.05)

Changes in mood and anxiety data were obtained at three and six months. Excluded from the analysis were patients who had had anticonvulsant drug or procedure changes at the time of antidepressant introduction. Improvements and/or remission of symptoms were observed in 86% of patients who continued in the study.

According to lead investigator Ramses Ribot, M.D., "SSRIs and SNRIs do not appear to worsen seizure frequency and yield a good therapeutic response independently of seizure frequency. Our studies also suggest these antidepressants may actually have an anti-seizure effect in patients with frequent seizures."

The findings are potentially of broad interest to treating physicians. However, the researchers say their findings need to be confirmed in prospective double-blind placebo-controlled clinical trials.


Story Source:

The above story is based on materials provided by American Epilepsy Society (AES). Note: Materials may be edited for content and length.


Cite This Page:

American Epilepsy Society (AES). "Do antidepressants improve mood and/or lessen seizure frequency in patients with epilepsy?." ScienceDaily. ScienceDaily, 3 December 2012. <www.sciencedaily.com/releases/2012/12/121203121444.htm>.
American Epilepsy Society (AES). (2012, December 3). Do antidepressants improve mood and/or lessen seizure frequency in patients with epilepsy?. ScienceDaily. Retrieved December 17, 2014 from www.sciencedaily.com/releases/2012/12/121203121444.htm
American Epilepsy Society (AES). "Do antidepressants improve mood and/or lessen seizure frequency in patients with epilepsy?." ScienceDaily. www.sciencedaily.com/releases/2012/12/121203121444.htm (accessed December 17, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, December 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com
When You Lose Weight, This Is Where The Fat Goes

When You Lose Weight, This Is Where The Fat Goes

Newsy (Dec. 17, 2014) Can fat disappear into thin air? New research finds that during weight loss, over 80 percent of a person's fat molecules escape through the lungs. Video provided by Newsy
Powered by NewsLook.com
Why Your Boss Should Let You Sleep In

Why Your Boss Should Let You Sleep In

Newsy (Dec. 17, 2014) According to research out of the University of Pennsylvania, waking up for work is the biggest factor that causes Americans to lose sleep. Video provided by Newsy
Powered by NewsLook.com
Flu Outbreak Closing Schools in Ohio

Flu Outbreak Closing Schools in Ohio

AP (Dec. 17, 2014) A wave of flu illnesses has forced some Ohio schools to shut down over the past week. State officials confirmed one pediatric flu-related death, a 15-year-old girl in southern Ohio. (Dec. 17) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins