Featured Research

from universities, journals, and other organizations

Frog-in-bucket-of-milk folklore leads to potential new antibiotics

Date:
December 12, 2012
Source:
American Chemical Society
Summary:
Following up on an ancient Russian way of keeping milk from going sour -- by putting a frog in the bucket of milk -- scientists have identified a wealth of new antibiotic substances in the skin of the Russian Brown frog.

Following up on an ancient Russian way of keeping milk from going sour -- by putting a frog in the bucket of milk -- scientists have identified a wealth of new antibiotic substances in the skin of the Russian Brown frog. The study appears in ACS' Journal of Proteome Research.

Related Articles


A. T. Lebedev and colleagues explain that amphibians secrete antimicrobial substances called peptides through their skin. These compounds make up the majority of their skin secretions and act as a first line of defense against bacteria and other microorganisms that thrive in the wet places frogs, toads, salamanders and other amphibians live. A previous study identified on the skin of the Russian Brown frog 21 substances with antibiotic and other potential medical activity. Lebedev's team set out to find more of these potential medical treasures.

They used a sensitive laboratory technique to expand the list of such substances on the frogs' skin, identifying 76 additional substances of this kind. They describe lab tests in which some of the substances performed as well against Salmonella and Staphylococcus bacteria as some prescription antibiotic medicines. "These peptides could be potentially useful for the prevention of both pathogenic and antibiotic resistant bacterial strains while their action may also explain the traditional experience of rural populations," the scientists concluded.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. T. Yu. Samgina, E. A Vorontsov, V. A. Gorshkov, E. Hakalehto, O. Hanninen, R. A. Zubarev, A. T. Lebedev. Composition and Antimicrobial Activity of the Skin Peptidome of Russian Brown FrogRana temporaria. Journal of Proteome Research, 2012; 121113155850001 DOI: 10.1021/pr300890m

Cite This Page:

American Chemical Society. "Frog-in-bucket-of-milk folklore leads to potential new antibiotics." ScienceDaily. ScienceDaily, 12 December 2012. <www.sciencedaily.com/releases/2012/12/121212130858.htm>.
American Chemical Society. (2012, December 12). Frog-in-bucket-of-milk folklore leads to potential new antibiotics. ScienceDaily. Retrieved October 24, 2014 from www.sciencedaily.com/releases/2012/12/121212130858.htm
American Chemical Society. "Frog-in-bucket-of-milk folklore leads to potential new antibiotics." ScienceDaily. www.sciencedaily.com/releases/2012/12/121212130858.htm (accessed October 24, 2014).

Share This



More Plants & Animals News

Friday, October 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Deep Sea 'mushroom' Could Be Early Branch on Tree of Life

Reuters - Innovations Video Online (Oct. 24, 2014) Miniature deep sea animals discovered off the Australian coast almost three decades ago are puzzling scientists, who say the organisms have proved impossible to categorise. Academics at the Natural History of Denmark have appealed to the world scientific community for help, saying that further information on Dendrogramma enigmatica and Dendrogramma discoides could answer key evolutionary questions. Jim Drury has more. Video provided by Reuters
Powered by NewsLook.com
Black Bear Cub Goes Sunday Shopping

Black Bear Cub Goes Sunday Shopping

Reuters - Light News Video Online (Oct. 23, 2014) Price check on honey? Bear cub startles Oregon drugstore shoppers. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
Dances With Wolves in China's Wild West

Dances With Wolves in China's Wild West

AFP (Oct. 23, 2014) One man is on a mission to boost the population of wolves in China's violence-wracked far west. The animal - symbol of the Uighur minority there - is under threat with a massive human resettlement program in the region. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
Breakfast Debate: To Eat Or Not To Eat?

Breakfast Debate: To Eat Or Not To Eat?

Newsy (Oct. 23, 2014) Conflicting studies published in the same week re-ignited the debate over whether we should be eating breakfast. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins