Featured Research

from universities, journals, and other organizations

Recurrence of small-for-gestational-age pregnancies confirmed

Date:
February 11, 2013
Source:
Society for Maternal-Fetal Medicine
Summary:
Findings suggest women with babies small-for-gestational-age in first pregnancy have increased risk for SGA in second.

In a study to be presented on Feb. 16 at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in San Francisco, researchers will report findings that suggest women whose babies are small-for-gestational-age (SGA) in their first pregnancy have a strongly increased risk for SGA in a second pregnancy.

The aim of this study was to assess and describe in detail the incidence of SGA infants and the SGA recurrence rate in general. Additionally, it sought to assess the incidence and recurrence rate of SGA in women with and without a hypertensive disorder in their first pregnancy.

Infants who are small for gestational age (birth weight below the fifth percentile) are a heterogeneous group comprising infants that have failed to achieve their growth potential (fetal growth restriction; FGR) and infants who are constitutionally small. SGA infants are at increased risk for perinatal mortality and adverse perinatal and health outcomes later in life.

"The main strength of this study was the size and composition of the cohort," said B J Voskamp, MD. "Data were derived from a large, well-maintained, population-based national perinatal registry."

The study was performed in a prospective nationwide cohort with the use of the Netherlands Perinatal Registry (PRN). The PRN consists of population-based data that includes information on pregnancy and delivery of 96 percent of pregnancies in the Netherlands. From this, they studied a cohort of women who delivered two subsequent singleton pregnancies (first and second deliveries) in the Netherlands from Jan. 1, 1999, through Dec. 31, 2007.

The primary outcome measure was SGA. Researchers registered demographic and obstetric characteristics including maternal age, parity, ethnicity, and socioeconomic status (SES).

Cases were analyzed in total and stratified into two groups: women with and without a hypertensive disorder in their first pregnancy. The analysis was stratified by gestational age at delivery in the first pregnancy in 3 groups: very preterm, late preterm, and full-term.

After exclusions, the study population comprised 259,481 women (518,962 deliveries). Five percent (12,943) of the women gave birth to SGA infants in their first pregnancy, and of those same women, SGA recurred in 2996 women (23.2 percent) in the subsequent pregnancy. SGA in the second pregnancy in women who had not previously had an SGA baby occurred in 3.4 percent of the women.

Further, the risk of SGA recurrence in women with hypertensive disorder in their first pregnancy was smaller than in women who did not. However, the risk of "de novo" SGA in the second pregnancy was higher for those with hypertensive disorder than their counterparts.


Story Source:

The above story is based on materials provided by Society for Maternal-Fetal Medicine. Note: Materials may be edited for content and length.


Cite This Page:

Society for Maternal-Fetal Medicine. "Recurrence of small-for-gestational-age pregnancies confirmed." ScienceDaily. ScienceDaily, 11 February 2013. <www.sciencedaily.com/releases/2013/02/130211110959.htm>.
Society for Maternal-Fetal Medicine. (2013, February 11). Recurrence of small-for-gestational-age pregnancies confirmed. ScienceDaily. Retrieved July 24, 2014 from www.sciencedaily.com/releases/2013/02/130211110959.htm
Society for Maternal-Fetal Medicine. "Recurrence of small-for-gestational-age pregnancies confirmed." ScienceDaily. www.sciencedaily.com/releases/2013/02/130211110959.htm (accessed July 24, 2014).

Share This




More Health & Medicine News

Thursday, July 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Idaho Boy Helps Brother With Disabilities Complete Triathlon

Newsy (July 23, 2014) An 8-year-old boy helped his younger brother, who has a rare genetic condition that's confined him to a wheelchair, finish a triathlon. Video provided by Newsy
Powered by NewsLook.com
Thousands Who Can't Afford Medical Care Flock to Free US Clinic

Thousands Who Can't Afford Medical Care Flock to Free US Clinic

AFP (July 23, 2014) America may be the world’s richest country, but in terms of healthcare, the World Health Organisation ranks it 37th. Thousands turned out for a free clinic run by "Remote Area Medical" with a visit from the Governor of Virginia. Duration: 2:40 Video provided by AFP
Powered by NewsLook.com
Stone Fruit Listeria Scare Causes Sweeping Recall

Stone Fruit Listeria Scare Causes Sweeping Recall

Newsy (July 22, 2014) The Wawona Packing Company has issued a voluntary recall on the stone fruit it distributes due to a possible Listeria outbreak. Video provided by Newsy
Powered by NewsLook.com
Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Huge Schizophrenia Study Finds Dozens Of New Genetic Causes

Newsy (July 22, 2014) The 83 new genetic markers could open dozens of new avenues for schizophrenia treatment research. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins