Featured Research

from universities, journals, and other organizations

Biting back: Snake venom contains toxic clotting factors

Date:
February 27, 2013
Source:
BioMed Central Limited
Summary:
The powerful venom of the saw-scaled viper Echis carinatus contains both anticoagulants and coagulants according to a new study. These may be a source of potent drugs to treat human disease. The saw-scaled viper family Echis, responsible for most snake attacks on humans, are recognizable by the ‘sizzling’ noise they make, produced by rubbing together special serrated scales, when threatened. Echis venom causes coagulopathy, which can result in symptoms ranging from lack of blood clotting, hemorrhage, renal failure and stroke.

The powerful venom of the saw-scaled viper Echis carinatus contains both anticoagulants and coagulants finds a study published in the launch edition of BioMed Central's open access journal Journal of Venomous Animals and Toxins including Tropical Diseases (JVATiTD). These may be a source of potent drugs to treat human disease.

The saw-scaled viper family Echis, responsible for most snake attacks on humans, are recognizable by the 'sizzling' noise they make, produced by rubbing together special serrated scales, when threatened. Echis venom causes coagulopathy, which can result in symptoms ranging from lack of blood clotting, hemorrhage, renal failure and stroke.

Researchers from the Razi Vaccine and Serum Research Institute, Iran led by Hossein Zolfagharian noted that treating plasma with venom from Echis carinatus actually causes it to coagulate. Splitting the venom by ion exchange chromatography showed that then venom contained both coagulants and anticoagulants. The clotting factors alone were toxic to mice.

The diametric effects of snake venom on blood are of interest because of medical applications, and although snakes can be considered as dangerous to humans -- they may yet save lives.

In the auspicious Year of the Snake, BioMed Central, the open access publisher, is pleased to announce that the Journal of Venomous Animals and Toxins including Tropical Diseases (JVATiTD), the official academic journal of the The Center for the Study of Venoms and Venomous Animals (CEVAP) of São Paulo State University (UNESP), based in Brazil, has moved to BioMed Central's open access publishing platform. Also this journal marks growth of BioMed Central's portfolio of open access journals to 250.

Along with research into snakes JVATiTD publishes studies into all aspects of toxins, venomous animals, and their derivative products, as well as tropical diseases especially infectious diseases, parasites and immunology.


Story Source:

The above story is based on materials provided by BioMed Central Limited. Note: Materials may be edited for content and length.


Journal Reference:

  1. Hossein Salmanizadeh, Mahdi Babaie and Hossein Zolfagharian. In vivo evaluation of homeostatic effects of Echis carinatus snake venom in Iran. Journal of Venomous Animals and Toxins including Tropical Diseases, 2013, 19:3 DOI: 10.1186/1678-9199-19-3

Cite This Page:

BioMed Central Limited. "Biting back: Snake venom contains toxic clotting factors." ScienceDaily. ScienceDaily, 27 February 2013. <www.sciencedaily.com/releases/2013/02/130226193845.htm>.
BioMed Central Limited. (2013, February 27). Biting back: Snake venom contains toxic clotting factors. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2013/02/130226193845.htm
BioMed Central Limited. "Biting back: Snake venom contains toxic clotting factors." ScienceDaily. www.sciencedaily.com/releases/2013/02/130226193845.htm (accessed July 31, 2014).

Share This




More Plants & Animals News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Visitors Feel Part of the Pack at Wolf Preserve

Visitors Feel Part of the Pack at Wolf Preserve

AP (July 31, 2014) — Seacrest Wolf Preserve on the northern Florida panhandle allows more than 10,000 visitors each year to get up close and personal with Arctic and British Columbian Wolves. (July 31) Video provided by AP
Powered by NewsLook.com
Florida Panther Rebound Upsets Ranchers

Florida Panther Rebound Upsets Ranchers

AP (July 31, 2014) — With Florida's panther population rebounding, some ranchers complain the protected predators are once again killing their calves. (July 31) Video provided by AP
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) — Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Raw: Thousands Flocking to German Crop Circle

Raw: Thousands Flocking to German Crop Circle

AP (July 30, 2014) — Thousands of people are trekking to a Bavarian farmer's field to check out a mysterious set of crop circles. (July 30) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



    Save/Print:
    Share:  

    Free Subscriptions


    Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

    Get Social & Mobile


    Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

    Have Feedback?


    Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
    Mobile iPhone Android Web
    Follow Facebook Twitter Google+
    Subscribe RSS Feeds Email Newsletters
    Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins