Featured Research

from universities, journals, and other organizations

Breath study brings roadside drug testing closer

Date:
April 25, 2013
Source:
Institute of Physics (IOP)
Summary:
A group of researchers from Sweden have provided further evidence that illegal drugs can be detected in the breath, opening up the possibility of a roadside breathalyzer test to detect substances such as cocaine, amphetamines and cannabis. Using a simple, commercially available breath sampler, the researchers have successfully identified a range of 12 substances in the breath of 40 patients recruited from a drug emergency clinic.

A group of researchers from Sweden have provided further evidence that illegal drugs can be detected in the breath, opening up the possibility of a roadside breathalyzer test to detect substances such as cocaine, amphetamines and cannabis.

Using a simple, commercially available breath sampler, the researchers have successfully identified a range of 12 substances in the breath of 40 patients recruited from a drug emergency clinic in Stockholm.

Their findings have been published today, 26 April, in IOP Publishing's Journal of Breath Research.

Blood, urine and saliva are the most popular methods for detecting illegal drugs and are already used by law enforcement in a number of countries; however, exhaled breath is seen as a promising alternative as it's easier to collect, non-invasive, less prone to adulteration and advantageous when location becomes an obstacle, such as at the roadside.

Exhaled breath contains very small particles that carry non-volatile substances from the airway lining fluid. Any compound that has been inhaled, or is present in the blood, may contaminate this fluid and pass into the breath when the airways open. The compounds will then be exhaled and can subsequently be detected.

In this study, researchers from the Karolinska Institute in Stockholm collected breath, blood plasma and urine samples from 47 patients (38 males, 9 females) who had taken drugs in the previous 24 hours and were recovering at a drug addiction emergency clinic.

Interviews were also undertaken with each patient to assess their history of drug use.

The breath samples were taken using a commercially available sampling device -- SensAbues -- and then analysed using liquid chromatography and mass spectrometry.

The portable sampling device consists of a mouth piece and a micro-particle filter. When a patient breathes into the mouth piece, saliva and larger particles are separated from the micro-particles that need to be measured.

The micro-particles are able to pass through and deposit onto a filter, which can then be sealed and stored ready for analysis. Breath samples were analysed for twelve substances.

Alprazolam and benzoylecgonine were detected in exhaled breath for the first time, whereas for methadone, amphetamine, methamphetamine, cocaine, morphine, 6-acetylmorphine, tetrahydrocannabinol, buprenorphine, diazepam and oxazepam, the results confirmed previous observations.

"Considering the samples were taken 24 hours after the intake of drugs, we were surprised to find that there was still high detectability for most drugs," said lead author of the study Professor Olof Beck.

"In cases of suspected driving under the influence of drugs, blood samples could be taken in parallel with breath when back at a police station. Future studies should therefore test the correlation between blood concentration of drugs of abuse and the concentrations in exhaled breath."


Story Source:

The above story is based on materials provided by Institute of Physics (IOP). Note: Materials may be edited for content and length.


Journal Reference:

  1. Olof Beck, Niclas Stephanson, Sören Sandqvist, Johan Franck. Detection of drugs of abuse in exhaled breath using a device for rapid collection: comparison with plasma, urine and self-reporting in 47 drug users. Journal of Breath Research, 2013; 7 (2): 026006 DOI: 10.1088/1752-7155/7/2/026006

Cite This Page:

Institute of Physics (IOP). "Breath study brings roadside drug testing closer." ScienceDaily. ScienceDaily, 25 April 2013. <www.sciencedaily.com/releases/2013/04/130425213901.htm>.
Institute of Physics (IOP). (2013, April 25). Breath study brings roadside drug testing closer. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2013/04/130425213901.htm
Institute of Physics (IOP). "Breath study brings roadside drug testing closer." ScienceDaily. www.sciencedaily.com/releases/2013/04/130425213901.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) — Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) — In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) — A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) — The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins