Featured Research

from universities, journals, and other organizations

Malaria: A vector infecting both apes and humans

Date:
May 3, 2013
Source:
Institut de Recherche pour le Développement (IRD)
Summary:
In 2010, a study revealed that the main agent of malaria in humans, called Plasmodium falciparum, arose from the gorilla. Today, the vector which transmitted the parasite from apes to humans has just been identified. Scientists have determined which species of anopheles mosquitoes transfer the disease to apes. Among them is Anopheles moucheti, known for biting humans. Therefore, it appears to be the species which originally infected us through our 'cousins'. And it could do it again today.

Gorillas are also infected.
Credit: © IRD / N. Rahola

In 2010, a study revealed that the main agent of malaria in humans, called Plasmodium falciparum, arose from the gorilla. Today, the vector which transmitted the parasite from apes to humans has just been identified. A Franco-Gabonese research consortium has determined which species of anopheles mosquitoes transfer the disease to apes. Among them is Anopheles moucheti, known for biting humans. Therefore, it appears to be the species which originally infected us through our cousins. And it could do it again today.

The same vector

IRD and CNRS researchers, in addition to their Gabonese partners based in the CIRMF in Franceville, wanted to determine the identity of the mosquitoes which transmit malaria to apes. To this end, they caught a thousand mosquitoes of the Anopheles genus, in close proximity to groups of wild or semi-wild primates. They then conducted analyses on the insects collected, belonging to fifteen different species, in order to detect which ones were infected by the Plasmodium malaria parasites. Two species of mosquitoes were thus revealed to be contaminated by these pathogenic agents. Anopheles moucheti was one of them -- a major vector for humans in Central Africa. This species is therefore both primatophilic and anthropophilic. Since gorillas are the origin of the disease in humans, this species would have enabled the transmission of the infection from apes to humans thousands of years ago.

A relatively unknown disease

Despite its major impact on public health, particularly in sub-Saharan Africa, there are still several grey areas regarding the parasite and its vector. In particular, how the disease is transmitted to great apes was a controversial question until now. By analogy with the transmission methods observed in humans, scientists guessed that the mosquitoes concerned belonged to the Anopheles genus. However, they still needed to identify the species responsible for contamination among great apes, or those species that transferred the infectious agents from gorillas to humans in the past.

The same parasites

Not long ago, the evolutionary history of pathogens was also unknown. Over the last 5 years, several species of Plasmodium were discovered in our close cousins, gorillas and chimpanzees. Researchers believed that some of them were specific to humans. In gorillas, they recently described P. praefalciparum, which is the closest genetic relative of P. falciparum, the most virulent infectious agent.

Anopheles moucheti could continue to transfer parasites from one mammal to another even today. As such, apes could be a reservoir for humans. The increasingly close interaction between humans and apes, due to deforestation and hunting activities, once again raises the question of the possible eradication of the disease. Conversely, the already documented transfer of the disease from humans to apes could also occur, thereby threatening populations that are already highly endangered.


Story Source:

The above story is based on materials provided by Institut de Recherche pour le Développement (IRD). Note: Materials may be edited for content and length.


Journal Reference:

  1. Christophe Paupy, Boris Makanga, Benjamin Ollomo, Nil Rahola, Patrick Durand, Julie Magnus, Eric Willaume, François Renaud, Didier Fontenille, Franck Prugnolle. Anopheles moucheti and Anopheles vinckei Are Candidate Vectors of Ape Plasmodium Parasites, Including Plasmodium praefalciparum in Gabon. PLoS ONE, 2013; 8 (2): e57294 DOI: 10.1371/journal.pone.0057294

Cite This Page:

Institut de Recherche pour le Développement (IRD). "Malaria: A vector infecting both apes and humans." ScienceDaily. ScienceDaily, 3 May 2013. <www.sciencedaily.com/releases/2013/05/130503094708.htm>.
Institut de Recherche pour le Développement (IRD). (2013, May 3). Malaria: A vector infecting both apes and humans. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2013/05/130503094708.htm
Institut de Recherche pour le Développement (IRD). "Malaria: A vector infecting both apes and humans." ScienceDaily. www.sciencedaily.com/releases/2013/05/130503094708.htm (accessed October 20, 2014).

Share This



More Plants & Animals News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Raw: Rare Lion Cubs Make Debut at Belgrade Zoo

Raw: Rare Lion Cubs Make Debut at Belgrade Zoo

AP (Oct. 17, 2014) — Two white lion cubs were born in Belgrade zoo three weeks ago. White lions are a rare mutation of a species found in South Africa and some cultures consider them divine. (Oct. 17) Video provided by AP
Powered by NewsLook.com
The Best Foods To Boost Your Mood

The Best Foods To Boost Your Mood

Buzz60 (Oct. 17, 2014) — Feeling down? Reach for the refrigerator, not the medicine cabinet! TC Newman (@PurpleTCNewman) shares some of the best foods to boost your mood. Video provided by Buzz60
Powered by NewsLook.com
Sweet Times for Hard Cider Makers

Sweet Times for Hard Cider Makers

AP (Oct. 16, 2014) — With hard cider making a hardcore comeback across the country, craft makers are trying to keep up with demand and apple growers are tapping a juicy new revenue stream. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Meet Garfi the Angry Cat

Meet Garfi the Angry Cat

Buzz60 (Oct. 16, 2014) — Garfi is one frowny, feisty feline - downright angry! Ko Im (@koimtv) introduces us to the latest animal celebrity taking over the Internet. You can follow more of Garfi's adventures on Twitter (@MeetGarfi) and Facebook (Garfi). Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Plants & Animals

Earth & Climate

Fossils & Ruins

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins