Featured Research

from universities, journals, and other organizations

MRI-based measurement helps predict vascular disease in the brain

Date:
May 23, 2013
Source:
Radiological Society of North America
Summary:
Aortic arch pulse wave velocity, a measure of arterial stiffness, is a strong independent predictor of disease of the vessels that supply blood to the brain, according to a new study.

Aortic arch pulse wave velocity, a measure of arterial stiffness, is a strong independent predictor of disease of the vessels that supply blood to the brain, according to a new study published in the June issue the journal Radiology.

"Pulse wave velocity from the aortic arch provides functional information about vessel compliance that may help determine a patient's risk for cerebrovascular disease down the road," said Kevin S. King, M.D., assistant professor of radiology at UT Southwestern Medical Center in Dallas.

Recent studies have shown an association between aortic stiffness and cerebrovascular disease. Dr. King and colleagues set out to evaluate the relationship between aortic arch pulse wave velocity and subsequent cerebral microvascular disease, independent of other cardiovascular risk factors, among 1,270 participants in the multiethnic Dallas Heart Study.

Aortic arch pulse wave velocity was measured with phase-contrast magnetic resonance imaging (MRI). Seven years later, the volume of white matter hyperintensities was determined using brain MRI. White matter hyperintensities, which appear as bright spots on brain MR images, are associated with accelerated motor and cognitive decline, Alzheimer's disease, stroke and death.

The researchers also analyzed 15 other cardiovascular risk factors, as well as age, gender and ethnicity, as predictors of white matter hyperintensities.

The results showed that aortic arch pulse wave velocity helped predict white matter hyperintensity volume, independent of the other demographic and cardiovascular risk factors. The researchers estimated that a one percent increase in aortic arch pulse wave velocity (in meters per second) is related to a 0.3 percent increase in subsequent white matter hyperintensity volume (in milliliters) when all other variables are constant.

"Our results demonstrate that aortic arch pulse wave velocity is a highly significant independent predictor of subsequent white matter hyperintensity volume and provides a distinct contribution -- along with systolic blood pressure, hypertension treatment, congestive heart failure and age -- in predicting risk for cerebrovascular disease," Dr. King said.


Story Source:

The above story is based on materials provided by Radiological Society of North America. Note: Materials may be edited for content and length.


Journal Reference:

  1. K. S. King, K. X. Chen, K. M. Hulsey, R. W. McColl, M. F. Weiner, P. A. Nakonezny, R. M. Peshock. White Matter Hyperintensities: Use of Aortic Arch Pulse Wave Velocity to Predict Volume Independent of Other Cardiovascular Risk Factors. Radiology, 2013; 267 (3): 709 DOI: 10.1148/radiol.13121598

Cite This Page:

Radiological Society of North America. "MRI-based measurement helps predict vascular disease in the brain." ScienceDaily. ScienceDaily, 23 May 2013. <www.sciencedaily.com/releases/2013/05/130523143727.htm>.
Radiological Society of North America. (2013, May 23). MRI-based measurement helps predict vascular disease in the brain. ScienceDaily. Retrieved August 21, 2014 from www.sciencedaily.com/releases/2013/05/130523143727.htm
Radiological Society of North America. "MRI-based measurement helps predict vascular disease in the brain." ScienceDaily. www.sciencedaily.com/releases/2013/05/130523143727.htm (accessed August 21, 2014).

Share This




More Health & Medicine News

Thursday, August 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com
Lost Brain Cells To Blame For Sleep Problems Among Seniors

Lost Brain Cells To Blame For Sleep Problems Among Seniors

Newsy (Aug. 21, 2014) According to a new study, elderly people might have trouble sleeping because of the loss of a certain group of neurons in the brain. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins